ASIP

Gene Symbol	ASIP
Entrez Gene	434
Alt Symbol	AGSW, AGTI, AGTIL, ASP, SHEP9
Species	Human
Gene Type	protein-coding
Description	agouti signaling protein
Other Description	agouti signaling protein, nonagouti homolog|agouti switch protein|agouti-signaling protein|nonagouti homolog
Swissprots	P42127 Q3SXL2
Accessions	AAA89208 AAB61247 EAW76282 P42127 AY805393 BC104238 AAI04239 BC104239 AAI04240 XM_005260412 XP_005260469 XM_011528820 XP_011527122 XM_011528821 XP_011527123 XM_011528822 XP_011527124 XM_011528823 XP_011527125 NM_001672 NP_001663
Function	Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.
Subcellular Location	Secreted.
Tissue Specificity	Expressed in adipose tissue, testis, ovary and heart and at lower levels in liver, kidney and foreskin.
Top Pathways	Melanogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ASP ELISA Kit - abx054831 from Abbexa Category ELISA Kit

Human ASP ELISA Kit - abx150755 from Abbexa Category ELISA Kit Sensitivity 0.073 ng/ml Range 0.156 ng/ml - 10 ng/ml

Abnormal spindle-like microcephaly-associated protein (ASPM), Human, ELISA Kit - CSB-EL002229HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Acylation stimulating protein (ASP), Human, ELISA Kit - CSB-E13474h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Acylation Stimulating Protein (ASP), Human, ELISA Kit - SEB238Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.073ng/mL Range 0.156-10ng/mL

Agouti-signaling protein (ASIP), Human, ELISA Kit - CSB-EL002212HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Agouti-signaling protein (ASIP), Human, ELISA Kit - E01A1721 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

ASP (Acylation Stimulating Protein), Human, ELISA Kit - E-EL-H0512 from ARP American Research Products Category ELISA Kit Prices $617.40 Sizes 96 t Sensitivity 46.875 pg/mL Range 78.125-5000pg/mL

Complement Component 3 (C3), Human, ELISA Kit - SEA861Hu from ARP American Research Products Category ELISA Kit Prices $459.00 Sizes 96 t Sensitivity 2.8ng/mL Range 7.8-500ng/mL

ASP (Acylation Stimulating Protein), Rabbit, ELISA Kit - E-EL-RB1668 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

ASP (Acylation Stimulating Protein), Chicken, ELISA Kit - E-EL-Ch2167 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

ASP (Acylation Stimulating Protein), Pig, ELISA Kit - E-EL-P1672 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

ASP (Acylation Stimulating Protein), Monkey, ELISA Kit - E-EL-MK1253 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

Human ASP ELISA Kit - HA0889 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine ASP ELISA Kit - AA0889 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human ASP (Acylation Stimulating Protein) CLIA Kit - E-CL-H0416 from Elabscience Category CLIA Kit Sensitivity 46.875pg/mL Range 78.125~5000pg/mL

agouti signaling protein, nonagouti homolog (mouse) , ELISA Kit - MBS907464 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human ASIP is typically less than 0.039 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.156 ng/ml -10 ng/ml.

Agouti-signaling protein, ELISA Kit - MBS281931 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Agouti-signaling protein (ASIP), ELISA Kit - MBS7242258 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Agouti-signaling protein (ASIP), ELISA Kit - MBS7228722 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Agouti-signaling protein (ASIP), ELISA Kit - MBS7211574 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Agouti-signaling protein (ASIP), ELISA Kit - MBS7209277 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Agouti-signaling protein (ASIP), ELISA Kit - MBS7203911 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Agouti-signaling protein (ASIP), ELISA Kit - MBS7218306 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Agouti-signaling protein (ASIP), ELISA Kit - MBS7230355 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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