PITPNM1

Gene Symbol PITPNM1
Entrez Gene 9600
Alt Symbol DRES9, NIR2, PITPNM, RDGB, RDGB1, RDGBA, RDGBA1, Rd9
Species Human
Gene Type protein-coding
Description phosphatidylinositol transfer protein, membrane-associated 1
Other Description NIR-2|PITPnm 1|PYK2 N-terminal domain-interacting receptor 2|drosophila retinal degeneration B homolog|membrane-associated phosphatidylinositol transfer protein 1|retinal degeneration B alpha 1
Swissprots Q9BZ73 Q8TBN3 Q6T7X3 O00562 A6NME4
Accessions EAW74638 EAW74639 EAW74640 EAW74641 EAW74642 EAW74643 O00562 AA465501 AF334584 AAK01444 AK126944 BAG54406 AK312886 BAG35734 AY429102 AAR06909 BC022230 AAH22230 DA318858 DQ891183 ABM82109 EU176563 ABW03364 X98654 CAA67224 XM_011545396 XP_011543698 XM_011545397 XP_011543699 XM_011545398 XP_011543700 XR_950112 XR_950113 NM_001130848 NP_001124320 NM_004910 NP_004901
Function Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions. {ECO:0000250, ECO:0000269|PubMed:10022914, ECO:0000269|PubMed:11909959, ECO:0000269|PubMed:15545272, ECO:0000269|PubMed:15723057}.
Subcellular Location Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Lipid droplet. Cleavage furrow. Midbody. Note=Peripheral membrane protein associated with Golgi stacks in interphase cells. A minor proportion is associated with the endoplasmic reticulum. Associated with lipid droplets. Dissociates from the Golgi early on in mitosis and localizes to the cleavage furrow and midbody during cytokinesis.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:10022914}.

Nir2 (G-20) - sc-23663 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Nir2 (H-101) - sc-368499 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Nir2 (H-101): sc-368499. Western blot analysis of Nir2 expression in rat cerebellum tissue extract.

Nir2 (N-18) - sc-23662 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-NIR2 antibody - ab22823 from Abcam

Prices $380.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab22823 (1/200) staining NIR2 in mouse macrophage cells by ICC/IF. Secondary antibody: donkey polyclonal to goat IgG conjugated to Alexa Fluor® 594; Counterstain: DAPI (blue) - please refer to abrevew for further details.See Abreview

Anti-NIR2 antibody - ab168646 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-NIR2 antibody (ab168646) at 1 µg/mlLane 1 : NIR2 transfected 293T cell lysate Lane 2 : Non-transfected 293T cell lysate Lysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-NIR2 antibody - ab118240 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-NIR2 antibody (ab118240) at 1/500 dilution + Human fetal brain lysate.

Anti-NIR2 antibody - ab130730 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-NIR2 antibody (ab130730) at 1/100 dilution + ZR-75-1 cell line lysate at 35 µg

Anti-PITPNM1 / NIR2 Antibody - LS-C190001 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody - LS-C190002 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody - LS-C190003 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody - LS-C190004 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody - LS-C210946 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody (HRP) - LS-C210948 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody (FITC) - LS-C210949 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody (aa142-171, AP) - LS-C266392 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody (Biotin) - LS-C210950 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody (aa142-171, APC) - LS-C266393 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody (aa142-171, PE) - LS-C266394 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody (aa142-171) - LS-C324060 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody (aa117-166) - LS-C135617 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PITPNM1 / NIR2 antibody LS-C135617 Western blot of Fetal Heart lysate.

Anti-PITPNM1 / NIR2 Antibody (aa143-171) - LS-C158663 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PITPNM1 Antibody western blot of mouse NIH-3T3 cell line lysates (35 ug/lane). The PITPNM1 antibody detected the PITPNM1 protein (arrow).

Anti-PITPNM1 / NIR2 Antibody (aa213-468) - LS-C178695 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PITPNM1 / NIR2 Antibody (aa1232-1244) - LS-C55290 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

NIR2 Antibody - NBP2-34132 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NIR2 Antibody [NBP2-34132] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4

NIR2 Antibody - H00009600-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: NIR2 Antibody [H00009600-B01] - analysis of PITPNM1 expression in transfected 293T cell line by PITPNM1 MaxPab polyclonal antibody (B01). Lane 1: PITPNM1 transfected lysate (134.80 KDa). Lane 2: Non-transfected lysate.
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