PITPNM1

Gene Symbol PITPNM1
Entrez Gene 9600
Alt Symbol DRES9, NIR2, PITPNM, RDGB, RDGB1, RDGBA, RDGBA1, Rd9
Species Human
Gene Type protein-coding
Description phosphatidylinositol transfer protein, membrane-associated 1
Other Description NIR-2|PITPnm 1|PYK2 N-terminal domain-interacting receptor 2|drosophila retinal degeneration B homolog|membrane-associated phosphatidylinositol transfer protein 1|retinal degeneration B alpha 1
Swissprots Q9BZ73 Q8TBN3 Q6T7X3 O00562 A6NME4
Accessions EAW74638 EAW74639 EAW74640 EAW74641 EAW74642 EAW74643 O00562 AA465501 AF334584 AAK01444 AK126944 BAG54406 AK312886 BAG35734 AY429102 AAR06909 BC022230 AAH22230 DA318858 DQ891183 ABM82109 EU176563 ABW03364 X98654 CAA67224 XM_011545396 XP_011543698 XM_011545397 XP_011543699 XM_011545398 XP_011543700 XR_950112 XR_950113 NM_001130848 NP_001124320 NM_004910 NP_004901
Function Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions. {ECO:0000250, ECO:0000269|PubMed:10022914, ECO:0000269|PubMed:11909959, ECO:0000269|PubMed:15545272, ECO:0000269|PubMed:15723057}.
Subcellular Location Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Lipid droplet. Cleavage furrow. Midbody. Note=Peripheral membrane protein associated with Golgi stacks in interphase cells. A minor proportion is associated with the endoplasmic reticulum. Associated with lipid droplets. Dissociates from the Golgi early on in mitosis and localizes to the cleavage furrow and midbody during cytokinesis.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:10022914}.

PITPNM1 293T Cell Transient Overexpression Lysate(Denatured) - H00009600-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

NIR2 Overexpression Lysate (Denatured) - H00009600-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
PITPNM1 transfected lysate.

Panoply™ Human PITPNM1 Knockdown Stable Cell Line - CSC-DC011821 from Creative biogene

Category Cell Line
Species Human
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