PITPNM1

Gene Symbol	PITPNM1
Entrez Gene	9600
Alt Symbol	DRES9, NIR2, PITPNM, RDGB, RDGB1, RDGBA, RDGBA1, Rd9
Species	Human
Gene Type	protein-coding
Description	phosphatidylinositol transfer protein, membrane-associated 1
Other Description	NIR-2|PITPnm 1|PYK2 N-terminal domain-interacting receptor 2|drosophila retinal degeneration B homolog|membrane-associated phosphatidylinositol transfer protein 1|retinal degeneration B alpha 1
Swissprots	Q9BZ73 Q8TBN3 Q6T7X3 O00562 A6NME4
Accessions	EAW74638 EAW74639 EAW74640 EAW74641 EAW74642 EAW74643 O00562 AA465501 AF334584 AAK01444 AK126944 BAG54406 AK312886 BAG35734 AY429102 AAR06909 BC022230 AAH22230 DA318858 DQ891183 ABM82109 EU176563 ABW03364 X98654 CAA67224 XM_011545396 XP_011543698 XM_011545397 XP_011543699 XM_011545398 XP_011543700 XR_950112 XR_950113 NM_001130848 NP_001124320 NM_004910 NP_004901
Function	Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions. {ECO:0000250, ECO:0000269|PubMed:10022914, ECO:0000269|PubMed:11909959, ECO:0000269|PubMed:15545272, ECO:0000269|PubMed:15723057}.
Subcellular Location	Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Lipid droplet. Cleavage furrow. Midbody. Note=Peripheral membrane protein associated with Golgi stacks in interphase cells. A minor proportion is associated with the endoplasmic reticulum. Associated with lipid droplets. Dissociates from the Golgi early on in mitosis and localizes to the cleavage furrow and midbody during cytokinesis.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:10022914}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NIR2 peptide - ab45570 from Abcam Category Peptide Species Human

Human NIR2 protein fragment - ab127088 from Abcam Category Protein Source E. coli Species Human

PITPNM1 / NIR2 Antibody Blocking Peptide - LS-E4864 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PITPNM1 / NIR2 Antibody Blocking Peptide - LS-E25703 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PITPNM1 / NIR2 Antibody Blocking Peptide - LS-E21884 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NIR2 Protein - H00009600-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PITPNM1-Antibody-N-term-Blocking-Peptide - BP17243a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PITPNM/PITPNM1 blocking peptide - GTX89678-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Bovine

Human PITPNM1 protein - orb245107 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

PITPNM1 Blocking Peptide - 33R-7011 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NIR2 Peptide - AC21-0533-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NIR2 - H00009600-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NIR2 - H00009600-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PITPNM Peptide - 46-195P from ProSci Category Peptide Species Mouse

PITPNM1 fusion protein - ag3947 from Proteintech Group Category Protein Source E. coli-derived, T-HIS Species Human

Recombinant human Membrane-associated phosphatidylinositol transfer protein 1 pr - CSB-EP019954h CSB-BP019954h CSB-MP019954h from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Membrane-associated phosphatidylinositol transfer protein 1(PITPNM1),partial - CSB-RP019954h from Cusabio Category Protein Source E.coli Species Human

Recombinant Human Membrane-associated phosphatidylinositol transfer protein 1(PITPNM1) ,partial - CSB-YP018038HU CSB-EP018038HU CSB-BP018038HU CSB-MP018038HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NIR2 (transcript variant 1) - TP304440 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PITPNM/PITPNM1, Peptide - MBS426114 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Dog, Bovine

NIR2 Recombinant Protein Antigen - NBP2-34132PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PITPNM1 Peptide, Human - M34GP11821H from Creative Peptides Category Peptide Source Synthetic. Species Human

PITPNM1 fusion protein - Ag25357 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant human Membrane-associated phosphatidylinositol transfer protein 1 - AP71746 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

NIR2 Recombinant Protein Antigen - NBP2-56687PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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