PSPC1

Gene Symbol PSPC1
Entrez Gene 55269
Alt Symbol PSP1
Species Human
Gene Type protein-coding
Description paraspeckle component 1
Other Description paraspeckle protein 1
Swissprots Q8WXE8 Q9NV36 Q8WXF1 Q5JTQ3 Q8NCZ9
Accessions EAX08232 EAX08233 EAX08234 Q8WXF1 AF448795 AAL59601 AF449627 AAL59602 AK001817 BAA91924 AK090873 AK301554 BAG63050 AL834505 CAD39162 BC014184 AAH14184 BM981042 BP225439 BQ685330 CA425205 CB214993 CR457272 CAG33553 CX759783 DA644474 DC396174 DQ892679 ABM83605 DQ895922 ABM86848 XM_006719844 XP_006719907 XM_011535137 XP_011533439 XM_011535138 XP_011533440 XM_011535139 XP_011533441 XM_011535140 XP_011533442 XM_011535141 XP_011533443 XM_011535142 XP_011533444 XM_011535143 XP_011533445 XR_941616 XR_941617 XR_941619 NM_001042414 NP_001035879 NR_003272 NR_044998
Function Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line (By similarity). Binds to poly(A), poly(G) and poly(U) RNA homopolymers. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Together with NONO, required for the formation of nuclear paraspeckles. {ECO:0000250, ECO:0000269|PubMed:22416126}.
Subcellular Location Nucleus, nucleolus. Nucleus matrix {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus speckle. Note=In punctate subnuclear structures often located adjacent to splicing speckles, called paraspeckles. Colocalizes with NONO and SFPQ in paraspeckles and perinucleolar caps in an RNA-dependent manner. May cycles between paraspeckles and nucleolus. In telophase, when daughter nuclei form, localizes to perinucleolar caps.
Tissue Specificity Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart. {ECO:0000269|PubMed:11790299}.

PSPC1 fusion protein - Ag11135 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

PSPC1 fusion protein - Ag10136 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human PSPC1, His-tagged - PSPC1-2038H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Paraspeckle component 1(PSPC1) - CSB-YP018937HU CSB-EP018937HU CSB-BP018937HU CSB-MP018937HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

PSPC1 / PSP1 (transcript variant alpha) - TP323202 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
PSPC1 / PSP1

Paraspeckle component 1 (PSPC1), Recombinant Protein - MBS1375082 from MyBioSource

Category Protein
Prices $1,315.00, $1,315.00, $1,530.00, $1,530.00, $2,165.00, $2,165.00, $2,630.00, $2,630.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

PSPC1 Recombinant Protein Antigen - NBP1-83801PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PSPC1-Antibody-C-term-Blocking-peptide - BP5582b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PSPC1 Peptide, Human - M34GP12627H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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