NFATC2IP

Gene Symbol	NFATC2IP
Entrez Gene	84901
Alt Symbol	ESC2, NIP45, RAD60
Species	Human
Gene Type	protein-coding
Description	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
Other Description	45 kDa NF-AT-interacting protein|45 kDa NFAT-interacting protein|NFATC2-interacting protein|nuclear factor of activated T-cells, cytoplasmic 2-interacting protein
Swissprots	Q8NFR2 Q6NVK1 Q8NCF5 Q66K34 B7Z4G5 Q96ST9
Accessions	CAF86795 EAW52014 EAW52015 Q8NCF5 AF458593 AAM49721 AK027545 BAB55189 AK074761 BAC11189 AK094764 AK297333 BAH12551 AK304172 BAH14125 AK304606 BAH14223 AK316535 BAH14906 AL043335 BC010161 BC018311 AAH18311 BC021551 AAH21551 BC068007 AAH68007 BC080628 AAH80628 BC101741 AAI01742 BC112182 AAI12183 XR_950864 NM_032815 NP_116204
Function	In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'- methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity). Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NFATC2IP full length protein - ab164685 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human NFATC2IP Protein - H00084901-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NFATC2IP - H00084901-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NFATC2IP - H00084901-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NFATC2IP fusion protein - Ag2217 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, T-HIS Species Human

Recombinant Human NFATC2IP, His-tagged - NFATC2IP-1274H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human NFATC2-interacting protein(NFATC2IP) - CSB-YP822758HU CSB-EP822758HU CSB-BP822758HU CSB-MP822758HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NFATC2IP Peptide, Human - M34GP10329H from Creative Peptides Category Peptide Source Synthetic. Species Human

NFATC2IP Recombinant Protein Antigen - NBP2-58210PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NFATC2-interacting protein (NFATC2IP), Recombinant Protein - MBS1476239 from MyBioSource Category Protein Prices $1,195.00, $1,195.00, $1,415.00, $1,415.00, $1,925.00, $1,925.00, $2,390.00, $2,390.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Protein ESC2 (ESC2), Recombinant Protein - MBS1403894 from MyBioSource Category Protein Prices $1,180.00, $1,180.00, $1,400.00, $1,400.00, $1,895.00, $1,895.00, $2,360.00, $2,360.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Ashbya gossypii

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