PPARD

Gene Symbol PPARD
Entrez Gene 5467
Alt Symbol FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB
Species Human
Gene Type protein-coding
Description peroxisome proliferator-activated receptor delta
Other Description PPAR-beta|PPAR-delta|nuclear hormone receptor 1|nuclear receptor subfamily 1 group C member 2|peroxisome proliferator-activated nuclear receptor beta/delta variant 2|peroxisome proliferator-activated receptor beta
Swissprots Q5D1P0 Q7Z5K0 E9PE18 Q03181 B6ZGS1 B4E3V3 A8K6J6 B7Z3W1 Q9BUD4
Accessions AAF62553 AAR05439 CAD55573 CBX54351 EAX03825 EAX03826 EAX03827 EAX03828 Q03181 AB099507 BAC78903 AB307691 BAH02282 AK122614 BAG53624 AK291661 BAF84350 AK296425 BAH12347 AK304482 BAG65293 AK304878 BAG65615 AY919140 AAX14041 AY927506 BC002715 AAH02715 BC007578 AAH07578 BC127809 BE503383 BQ441091 CN332566 DA192442 DA476590 HQ692865 ADZ17376 L07592 AAA36469 XM_005249193 XP_005249250 XM_006715120 XP_006715183 XM_006715121 XP_006715184 XM_006715123 XP_006715186 XM_011514707 XP_011513009 XM_011514708 XP_011513010 XM_011514709 XP_011513011 XM_011514710 XP_011513012 XM_011514711 XP_011513013 XM_011514712 XP_011513014 XM_011514713 XP_011513015 NM_001171818 NP_001165289 NM_001171819 NP_001165290 NM_001171820 NP_001165291 NM_006238 NP_006229 NM_177435 NP_803184
Function Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand. {ECO:0000269|PubMed:1333051, ECO:0000269|PubMed:15604518}.
Subcellular Location Nucleus.
Tissue Specificity Ubiquitous with maximal levels in placenta and skeletal muscle.
Top Pathways Wnt signaling pathway, Acute myeloid leukemia, PPAR signaling pathway

PPARβ (F-10) - sc-74517 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PPARβ (F-10): sc-74517. Western blot analysis of PPARβ expression in Jurkat nuclear extract.

PPARβ (F-7) - sc-74440 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PPARβ (F-7): sc-74440. Western blot analysis of human recombinant PPARβ fusion protein.

PPARβ (H-74) - sc-7197 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PPARβ (H-74): sc-7197. Immunofluorescence staining of methanol-fixed Sol8 cells showing nuclear localization.

PPARβ (N-20) - sc-1986 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PPARβ (K-20) - sc-1987 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PPARβ (K-20): sc-1987. Western blot analysis of human recombinant PPARβ fusion protein.

PPARβ (C-20) - sc-1983 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PPAR delta antibody - ab8937 from Abcam

Prices $391.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab8937 stained HepG2 cells (ab7900). The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum (ab7481) / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab8937, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-PPAR delta antibody [4E3-1B11] - ab58137 from Abcam

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4E3-1B11

Anti-PPAR delta antibody - ab125290 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PPAR delta antibody (ab125290) at 1/500 dilutionLane 1 : HT29 whole cell lysateLane 2 : HT29 whole cell lysate with immunizing antigen

Anti-PPAR delta antibody - ab58139 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PPAR delta antibody [EPR5185(2)] - ab173299 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5185(2)
All lanes : Anti-PPAR delta antibody [EPR5185(2)] (ab173299) at 1/1000 dilutionLane 1 : HCT-116 cell lysateLane 2 : K562 cell lysateLane 3 : Jurkat cell lysateLysates/proteins at 10 µg per lane.

Anti-PPARD / PPAR Delta Antibody (aa430-441) IHC-plus™ - LS-B3934 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-PPAR Delta antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3934 concentration 3.75 ug/ml.

Anti-PPARD / PPAR Delta Antibody (aa1-14) - LS-C9677 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PPARD / PPAR Delta Antibody (N-Terminus) - LS-C42582 from LifeSpan Bioscience

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PPARD / PPAR Delta Antibody (C-Terminus) - LS-C31049 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
LN18 Lysate

Anti-PPARD / PPAR Delta Antibody (aa144-193) - LS-C31047 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
SP2/0 Cell Lysate

Anti-PPARD / PPAR Delta Antibody (aa169-218) - LS-C31051 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Jurkat Cell Lysate

Anti-PPARD / PPAR Delta Antibody - LS-C84157 from LifeSpan Bioscience

Prices $755.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PPARD / PPAR Delta Antibody (aa1-14) - LS-C122329 from LifeSpan Bioscience

Prices $665.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PPARD / PPAR Delta Antibody (aa367-394, AP) - LS-C266786 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPARD / PPAR Delta Antibody (aa367-394, APC) - LS-C266787 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPARD / PPAR Delta Antibody (aa367-394, Biotin) - LS-C266788 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPARD / PPAR Delta Antibody (aa367-394, FITC) - LS-C266790 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPARD / PPAR Delta Antibody (N-Terminus) - LS-C110317 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PPARD antibody LS-C110317 Western blot of 721_B cell lysate.

Anti-PPARD / PPAR Delta Antibody (aa367-394, PE) - LS-C284683 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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