PPARD

Gene Symbol PPARD
Entrez Gene 5467
Alt Symbol FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB
Species Human
Gene Type protein-coding
Description peroxisome proliferator-activated receptor delta
Other Description PPAR-beta|PPAR-delta|nuclear hormone receptor 1|nuclear receptor subfamily 1 group C member 2|peroxisome proliferator-activated nuclear receptor beta/delta variant 2|peroxisome proliferator-activated receptor beta
Swissprots Q5D1P0 Q7Z5K0 E9PE18 Q03181 B6ZGS1 B4E3V3 A8K6J6 B7Z3W1 Q9BUD4
Accessions AAF62553 AAR05439 CAD55573 CBX54351 EAX03825 EAX03826 EAX03827 EAX03828 Q03181 AB099507 BAC78903 AB307691 BAH02282 AK122614 BAG53624 AK291661 BAF84350 AK296425 BAH12347 AK304482 BAG65293 AK304878 BAG65615 AY919140 AAX14041 AY927506 BC002715 AAH02715 BC007578 AAH07578 BC127809 BE503383 BQ441091 CN332566 DA192442 DA476590 HQ692865 ADZ17376 L07592 AAA36469 XM_005249193 XP_005249250 XM_006715120 XP_006715183 XM_006715121 XP_006715184 XM_006715123 XP_006715186 XM_011514707 XP_011513009 XM_011514708 XP_011513010 XM_011514709 XP_011513011 XM_011514710 XP_011513012 XM_011514711 XP_011513013 XM_011514712 XP_011513014 XM_011514713 XP_011513015 NM_001171818 NP_001165289 NM_001171819 NP_001165290 NM_001171820 NP_001165291 NM_006238 NP_006229 NM_177435 NP_803184
Function Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand. {ECO:0000269|PubMed:1333051, ECO:0000269|PubMed:15604518}.
Subcellular Location Nucleus.
Tissue Specificity Ubiquitous with maximal levels in placenta and skeletal muscle.
Top Pathways Wnt signaling pathway, Acute myeloid leukemia, PPAR signaling pathway

PPARβ siRNA (h) - sc-36305 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PPARβ shRNA Plasmid (h) - sc-36305-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PPARβ shRNA (h) Lentiviral Particles - sc-36305-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PPAR delta/NR1C2 RNAi - H00005467-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU058791 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2330 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2330 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10916 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10916

PPARD siRNA (Human) - CRH3667 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PPAR delta/NR1C2 RNAi - H00005467-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

Human PPARD siRNA - orb264169 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PPARD shRNA Plasmid (Human) - CHH3667 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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