Gene Symbol | TNFRSF13B |
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Entrez Gene | 23495 |
Alt Symbol | CD267, CVID, CVID2, IGAD2, RYZN, TACI, TNFRSF14B |
Species | Human |
Gene Type | protein-coding |
Description | tumor necrosis factor receptor superfamily, member 13B |
Other Description | transmembrane activator and CAML interactor|tumor necrosis factor receptor 13B|tumor necrosis factor receptor superfamily member 13B |
Swissprots | Q32LX4 Q7Z6F5 B7Z6V8 B2R8B0 O14836 |
Accessions | ABK41894 BAE16555 CAF03579 CAJ90562 CAJ90567 CAJ90607 CAJ90609 CAM32377 CAZ39523 CBH32710 CBH51785 CBI12200 CBI67647 CBX33267 CBY65601 CBY65603 EAW55728 EAW55729 O14836 AF023614 AAC51790 AK097261 AK223453 BAD97173 AK301032 BAH13394 AK313302 BAG36107 AX766384 CAE00326 AX772740 CAE06248 AY302137 AAP57629 BC109392 AAI09393 NM_012452 NP_036584 |
Function | Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T- cell function and the regulation of humoral immunity. {ECO:0000269|PubMed:10956646, ECO:0000269|PubMed:10973284}. |
Subcellular Location | Membrane; Single-pass type III membrane protein. |
Tissue Specificity | Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B- cells and activated T-cells, but not in resting T-cells. |
Top Pathways | Cytokine-cytokine receptor interaction, Primary immunodeficiency, Intestinal immune network for IgA production |
Human TACI protein fragment - ab50090 from Abcam
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Human TACI protein fragment - ab140539 from Abcam
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Human TACI protein fragment - ab191944 from Abcam
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TACI peptide - ab6244 from Abcam
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TNFRSF13B / TACI Antibody Blocking Peptide - LS-E23222 from LifeSpan Bioscience
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TNFRSF13B / TACI Antibody Blocking Peptide - LS-E29956 from LifeSpan Bioscience
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Recombinant Human TACI/TNFRSF13B/CVID Protein - NBP2-22903 from Novus Biologicals
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TACI/TNFRSF13B/CVID Peptide - NBP1-76779PEP from Novus Biologicals
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TACI Recombinant Protein (Active) - GTX48045-PRO from GeneTex
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TACI peptide - GTX26244 from GeneTex
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Recombinant Human TACI/TNFRSF13B Fc Chimera, CF - 174-TC-050 from R&D Systems
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Human CD267 protein - orb84408 from Biorbyt
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Human TNFRSF13B protein - orb180439 from Biorbyt
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Human TACI protein - orb169386 from Biorbyt
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Human TACI protein - orb223828 from Biorbyt
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TACI protein - 30R-AT076 from Fitzgerald
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TNFRSF13B protein (His tag) - 80R-2693 from Fitzgerald
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CD267 / TACI (1-165, His-tag) - AR50813PU-N from Acris Antibodies
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CD267 / TACI (1-165, His-tag) - AR50813PU-S from Acris Antibodies
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CD267 / TACI - PA196 from Acris Antibodies
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CD267 / TACI - PA196X from Acris Antibodies
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CD267 / TACI - H00023495-H01 from Acris Antibodies
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CD267 / TACI - P6161 from Acris Antibodies
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CD267 / TACI Control Peptide - AP30855CP-N from Acris Antibodies
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TACI (TNFRSF13B), Recombinant Human - 213-10421-1 from RayBiotech
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