TNFRSF13B

Gene Symbol TNFRSF13B
Entrez Gene 23495
Alt Symbol CD267, CVID, CVID2, IGAD2, RYZN, TACI, TNFRSF14B
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 13B
Other Description transmembrane activator and CAML interactor|tumor necrosis factor receptor 13B|tumor necrosis factor receptor superfamily member 13B
Swissprots Q32LX4 Q7Z6F5 B7Z6V8 B2R8B0 O14836
Accessions ABK41894 BAE16555 CAF03579 CAJ90562 CAJ90567 CAJ90607 CAJ90609 CAM32377 CAZ39523 CBH32710 CBH51785 CBI12200 CBI67647 CBX33267 CBY65601 CBY65603 EAW55728 EAW55729 O14836 AF023614 AAC51790 AK097261 AK223453 BAD97173 AK301032 BAH13394 AK313302 BAG36107 AX766384 CAE00326 AX772740 CAE06248 AY302137 AAP57629 BC109392 AAI09393 NM_012452 NP_036584
Function Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T- cell function and the regulation of humoral immunity. {ECO:0000269|PubMed:10956646, ECO:0000269|PubMed:10973284}.
Subcellular Location Membrane; Single-pass type III membrane protein.
Tissue Specificity Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B- cells and activated T-cells, but not in resting T-cells.
Top Pathways Cytokine-cytokine receptor interaction, Primary immunodeficiency, Intestinal immune network for IgA production

TACI CRISPR/Cas9 KO Plasmid (h) - sc-406692 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TACI HDR Plasmid (h) - sc-406692-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TACI Double Nickase Plasmid (h) - sc-406692-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TACI Double Nickase Plasmid (h2) - sc-406692-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TACI CRISPR Activation Plasmid (h) - sc-406692-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TACI CRISPR Activation Plasmid (h2) - sc-406692-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TACI Lentiviral Activation Particles (h) - sc-406692-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TACI Lentiviral Activation Particles (h2) - sc-406692-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TACI siRNA (h) - sc-40243 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TACI shRNA Plasmid (h) - sc-40243-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TACI shRNA (h) Lentiviral Particles - sc-40243-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TACI/TNFRSF13B/CVID RNAi - H00023495-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU120411 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21745 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21745 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05096 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05096

TNFRSF13B siRNA (Human) - CRH8305 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFRSF13B - MBS8237320 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TNFRSF13B (NM_012452.2) - SHH431908 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TNFRSF13B(NM_012452.2) - SHL084726 from Creative biogene

Category siRNA
Species Reactivities Human

Human TNFRSF13B siRNA - orb268807 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFRSF13B shRNA Plasmid (Human) - CHH8305 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TNFRSF13B miRNA 3'UTR clone - MiUTR1H-10594 from Creative biogene

Species Reactivities Human
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