Wtap

Gene Symbol	Wtap
Entrez Gene	60532
Alt Symbol	2810408K05Rik, 9430038B09Rik
Species	Mouse
Gene Type	protein-coding
Description	Wilms tumour 1-associating protein
Other Description	WT1-associated protein\|Wilms' tumour 1-associating protein\|female-lethal(2)D homolog\|pre-mRNA-splicing regulator WTAP\|wilms tumor 1-associating protein
Swissprots	Q9ER69 Q566J5 Q3U120
Accessions	EDL02020 EDL02021 EDL02023 Q9ER69 AJ276707 CAC16790 AK031965 AK041341 AK051702 AK076111 BAC36191 AK156334 BAE33680 AK220249 BAD90174 BC046416 AAH46416 BC047338 BC093504 AAH93504 BU516500 BY016042 XM_006523341 XP_006523404 NM_001113532 NP_001107004 NM_001113533 NP_001107005 NM_175394 NP_780603
Function	Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus, nucleolus {ECO:0000250}. Nucleus speckle {ECO:0000250}.

Category	Protein
Source	Yeast or E.coli or Baculovirus or Mammalian cell
Species	Mouse

Category	Protein
Prices	$1,170.00, $1,170.00, $1,395.00, $1,395.00, $1,870.00, $1,870.00, $2,335.00, $2,335.00
Sizes	500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source	E Coli or Yeast or Baculovirus or Mammalian Cell
Species	Mouse

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