Gene Symbol | TXNDC8 |
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Entrez Gene | 255220 |
Alt Symbol | SPTRX-3, TRX6, bA427L11.2 |
Species | Human |
Gene Type | protein-coding |
Description | thioredoxin domain containing 8 (spermatozoa) |
Other Description | sperm-specific thioredoxin 3|spermatid-specific thioredoxin-3|spermatocyte/spermatid-specific thioredoxin-3|thioredoxin 6|thioredoxin domain-containing protein 8 |
Swissprots | Q6A555 A6NDK7 Q5T934 A1L4I2 |
Accessions | EAW59061 Q6A555 AF305830 AAQ14501 BC035743 BC130549 AAI30550 BC130551 AAI30552 BC144461 AAI44462 HQ258720 ADR83471 HY007335 XM_011518459 XP_011516761 XM_011518460 XP_011516762 XM_011518461 XP_011516763 XM_011518462 XP_011516764 XM_011518463 XP_011516765 XM_011518464 XP_011516766 XR_929743 XR_929744 XR_929745 XR_929746 NM_001003936 NP_001003936 NM_001286946 NP_001273875 NM_001286947 NP_001273876 |
Function | May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15181017}. Golgi apparatus {ECO:0000269|PubMed:15181017}. |
Tissue Specificity | Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level). {ECO:0000269|PubMed:15181017}. |
Anti-TXNDC8 antibody - ab126382 from Abcam
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TXNDC8 Antibody - NBP1-92551 from Novus Biologicals
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Anti-TXNDC8 antibody produced in rabbit - HPA046844 from Sigma-Aldrich
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Anti-TXNDC8 (aa 1-63) polyclonal antibody - DPABH-22787 from Creative Diagnostics
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TXNDC8 Antibody,Biotin conjugated - CSB-PA718200LD01HU from Cusabio
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TXNDC8 Antibody,FITC conjugated - CSB-PA718200LC01HU from Cusabio
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TXNDC8 Antibody,HRP conjugated - CSB-PA718200LB01HU from Cusabio
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TXNDC8 Antibody - CSB-PA718200LA01HU from Cusabio
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Anti-TXNDC8 Antibody A13008 - A13008 from Boster Bio
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TXNDC8 Antibody - middle region (ARP79428_P050) - ARP79428_P050 from Aviva Systems Biology
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TXNDC8 antibody - C-terminal region (OAAB00941) - OAAB00941 from Aviva Systems Biology
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TXNDC8, Polyclonal Antibody - MBS7003195 from MyBioSource
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TXNDC8, Polyclonal Antibody - MBS7002216 from MyBioSource
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TXNDC8, Polyclonal Antibody - MBS7003052 from MyBioSource
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TXNDC8, Polyclonal Antibody - MBS7003821 from MyBioSource
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TXNDC8 antibody (HRP) - orb31072 from Biorbyt
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TXNDC8 antibody (FITC) - orb31076 from Biorbyt
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TXNDC8 antibody - orb31068 from Biorbyt
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