TXNDC8

Gene Symbol TXNDC8
Entrez Gene 255220
Alt Symbol SPTRX-3, TRX6, bA427L11.2
Species Human
Gene Type protein-coding
Description thioredoxin domain containing 8 (spermatozoa)
Other Description sperm-specific thioredoxin 3|spermatid-specific thioredoxin-3|spermatocyte/spermatid-specific thioredoxin-3|thioredoxin 6|thioredoxin domain-containing protein 8
Swissprots Q6A555 A6NDK7 Q5T934 A1L4I2
Accessions EAW59061 Q6A555 AF305830 AAQ14501 BC035743 BC130549 AAI30550 BC130551 AAI30552 BC144461 AAI44462 HQ258720 ADR83471 HY007335 XM_011518459 XP_011516761 XM_011518460 XP_011516762 XM_011518461 XP_011516763 XM_011518462 XP_011516764 XM_011518463 XP_011516765 XM_011518464 XP_011516766 XR_929743 XR_929744 XR_929745 XR_929746 NM_001003936 NP_001003936 NM_001286946 NP_001273875 NM_001286947 NP_001273876
Function May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15181017}. Golgi apparatus {ECO:0000269|PubMed:15181017}.
Tissue Specificity Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level). {ECO:0000269|PubMed:15181017}.

Sptrx-3 CRISPR/Cas9 KO Plasmid (h) - sc-417039 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-3 HDR Plasmid (h) - sc-417039-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-3 Double Nickase Plasmid (h) - sc-417039-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-3 Double Nickase Plasmid (h2) - sc-417039-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-3 CRISPR Activation Plasmid (h) - sc-417039-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-3 CRISPR Activation Plasmid (h2) - sc-417039-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-3 Lentiviral Activation Particles (h) - sc-417039-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-3 Lentiviral Activation Particles (h2) - sc-417039-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPTRX-3 siRNA (h) - sc-92636 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPTRX-3 shRNA Plasmid (h) - sc-92636-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPTRX-3 shRNA (h) Lentiviral Particles - sc-92636-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TXNDC8 RNAi - H00255220-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU228941 from Sigma-Aldrich

Category siRNA
Prices $140.00, $140.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22311 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22311 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TXNDC8 siRNA (Human) - CRJ6711 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TXNDC8 - MBS8241108 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Txndc8 (NM_001003936.2) - SHH438304 from Creative biogene

Category siRNA
Species Reactivities Human

Human TXNDC8 siRNA - orb277212 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TXNDC8 shRNA Plasmid (Human) - CHJ6711 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TXNDC8 miRNA 3'UTR clone - MiUTR4H-TG09538 from Creative biogene

Species Reactivities Human
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