Gene Symbol | UBXN4 |
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Entrez Gene | 23190 |
Alt Symbol | UBXD2, UBXDC1, erasin |
Species | Human |
Gene Type | protein-coding |
Description | UBX domain protein 4 |
Other Description | UBX domain containing 2|UBX domain-containing 1|UBX domain-containing protein 2|UBX domain-containing protein 4 |
Swissprots | Q4ZG56 A8K9W4 Q8IYM5 Q92575 |
Accessions | AAX88923 EAX11623 EAX11624 EAX11625 Q92575 AI039259 AK026971 AK095402 BAG53047 AK292829 BAF85518 AK304096 BAG65002 AK311058 AM392761 CAL37639 AM393478 CAL38355 BC020806 AAH20806 BC035594 AAH35594 BP247627 BX647216 BX647662 D87684 BAA13437 DQ891123 ABM82049 DQ894302 ABM85228 EF199840 ABM90426 NM_014607 NP_055422 |
Function | Involved in endoplasmic reticulum-associated protein degradation (ERAD). {ECO:0000269|PubMed:16968747}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16968747}; Peripheral membrane protein {ECO:0000269|PubMed:16968747}. Nucleus envelope {ECO:0000269|PubMed:16968747}. Note=Both the N- and the C-terminus face the cytosol. Also found in the nucleus envelope contiguous to the ER. |
Tissue Specificity | Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level). {ECO:0000269|PubMed:16968747}. |
erasin (D-16) - sc-161041 from Santa Cruz Biotechnology
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erasin (S-12) - sc-161043 from Santa Cruz Biotechnology
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erasin (X-25) - sc-133555 from Santa Cruz Biotechnology
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Anti-UBXD2 / UBXN4 Antibody (aa301-350) - LS-C81093 from LifeSpan Bioscience
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UBXD2 Antibody - NBP1-79240 from Novus Biologicals
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UBXD2 Antibody - NBP1-92560 from Novus Biologicals
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UBXD2 Polyclonal Antibody - bs-11675R from Bioss
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UBXD2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11675R-A350 from Bioss
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UBXD2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11675R-A488 from Bioss
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UBXD2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11675R-A555 from Bioss
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UBXD2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11675R-A647 from Bioss
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UBXD2 Polyclonal Antibody, Cy3 Conjugated - bs-11675R-Cy3 from Bioss
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UBXD2 Polyclonal Antibody, Cy5 Conjugated - bs-11675R-Cy5 from Bioss
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UBXD2 Polyclonal Antibody, Cy5.5 Conjugated - bs-11675R-Cy5.5 from Bioss
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UBXD2 Polyclonal Antibody, Cy7 Conjugated - bs-11675R-Cy7 from Bioss
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UBXD2 Polyclonal Antibody, FITC Conjugated - bs-11675R-FITC from Bioss
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UBXD2 Polyclonal Antibody, Biotin Conjugated - bs-11675R-Biotin from Bioss
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UBXD2 Polyclonal Antibody, HRP Conjugated - bs-11675R-HRP from Bioss
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Anti-UBXN4 antibody produced in rabbit - HPA036325 from Sigma-Aldrich
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Anti-UBXD2 antibody produced in rabbit - AV47620 from Sigma-Aldrich
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UBXD2 antibody - middle region (ARP47620_T100) - ARP47620_T100 from Aviva Systems Biology
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UBXN4 Antibody - C-terminal region (ARP75456_P050) - ARP75456_P050 from Aviva Systems Biology
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UBXN4 antibody - 70R-21136 from Fitzgerald
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UBXD2 antibody - 20R-1265 from Fitzgerald
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UBXN4 / UBXD2 antibody - 21052-1-AP from Acris Antibodies
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