Gene Symbol | UBXN4 |
---|---|
Entrez Gene | 23190 |
Alt Symbol | UBXD2, UBXDC1, erasin |
Species | Human |
Gene Type | protein-coding |
Description | UBX domain protein 4 |
Other Description | UBX domain containing 2|UBX domain-containing 1|UBX domain-containing protein 2|UBX domain-containing protein 4 |
Swissprots | Q4ZG56 A8K9W4 Q8IYM5 Q92575 |
Accessions | AAX88923 EAX11623 EAX11624 EAX11625 Q92575 AI039259 AK026971 AK095402 BAG53047 AK292829 BAF85518 AK304096 BAG65002 AK311058 AM392761 CAL37639 AM393478 CAL38355 BC020806 AAH20806 BC035594 AAH35594 BP247627 BX647216 BX647662 D87684 BAA13437 DQ891123 ABM82049 DQ894302 ABM85228 EF199840 ABM90426 NM_014607 NP_055422 |
Function | Involved in endoplasmic reticulum-associated protein degradation (ERAD). {ECO:0000269|PubMed:16968747}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16968747}; Peripheral membrane protein {ECO:0000269|PubMed:16968747}. Nucleus envelope {ECO:0000269|PubMed:16968747}. Note=Both the N- and the C-terminus face the cytosol. Also found in the nucleus envelope contiguous to the ER. |
Tissue Specificity | Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level). {ECO:0000269|PubMed:16968747}. |
erasin CRISPR/Cas9 KO Plasmid (h) - sc-411689 from Santa Cruz Biotechnology
|
||||||||
erasin HDR Plasmid (h) - sc-411689-HDR from Santa Cruz Biotechnology
|
||||||||
erasin Double Nickase Plasmid (h) - sc-411689-NIC from Santa Cruz Biotechnology
|
||||||||
erasin Double Nickase Plasmid (h2) - sc-411689-NIC-2 from Santa Cruz Biotechnology
|
||||||||
erasin CRISPR Activation Plasmid (h) - sc-411689-ACT from Santa Cruz Biotechnology
|
||||||||
erasin CRISPR Activation Plasmid (h2) - sc-411689-ACT-2 from Santa Cruz Biotechnology
|
||||||||
erasin Lentiviral Activation Particles (h) - sc-411689-LAC from Santa Cruz Biotechnology
|
||||||||
erasin Lentiviral Activation Particles (h2) - sc-411689-LAC-2 from Santa Cruz Biotechnology
|
||||||||
erasin siRNA (h) - sc-94539 from Santa Cruz Biotechnology
|
||||||||
erasin shRNA Plasmid (h) - sc-94539-SH from Santa Cruz Biotechnology
|
||||||||
erasin shRNA (h) Lentiviral Particles - sc-94539-V from Santa Cruz Biotechnology
|
||||||||
UBXD2 RNAi - H00023190-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU036361 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN22429 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22429 from Sigma-Aldrich
|
||||||||
UBXN4 siRNA (Human) - CRH8070 from Cohesion Biosciences
|
||||||||
UBXN4 - MBS8208238 from MyBioSource
|
||||||||
shRNA set against Human UBXN4 (NM_014607.3) - SHH439700 from Creative biogene
|
||||||||
Human UBXN4 siRNA - orb268572 from Biorbyt
|
||||||||
UBXN4 shRNA Plasmid (Human) - CHH8070 from Cohesion Biosciences
|
||||||||
UBXN4 miRNA 3'UTR clone - MiUTR1H-10971 from Creative biogene
|