| Gene Symbol |
UBXN4
|
| Entrez Gene |
23190
|
| Alt Symbol |
UBXD2, UBXDC1, erasin
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
UBX domain protein 4
|
| Other Description |
UBX domain containing 2|UBX domain-containing 1|UBX domain-containing protein 2|UBX domain-containing protein 4
|
| Swissprots |
Q4ZG56 A8K9W4 Q8IYM5 Q92575
|
| Accessions |
AAX88923 EAX11623 EAX11624 EAX11625 Q92575 AI039259 AK026971 AK095402 BAG53047 AK292829 BAF85518 AK304096 BAG65002 AK311058 AM392761 CAL37639 AM393478 CAL38355 BC020806 AAH20806 BC035594 AAH35594 BP247627 BX647216 BX647662 D87684 BAA13437 DQ891123 ABM82049 DQ894302 ABM85228 EF199840 ABM90426 NM_014607 NP_055422
|
| Function |
Involved in endoplasmic reticulum-associated protein degradation (ERAD). {ECO:0000269|PubMed:16968747}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:16968747}; Peripheral membrane protein {ECO:0000269|PubMed:16968747}. Nucleus envelope {ECO:0000269|PubMed:16968747}. Note=Both the N- and the C-terminus face the cytosol. Also found in the nucleus envelope contiguous to the ER.
|
| Tissue Specificity |
Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level). {ECO:0000269|PubMed:16968747}.
|
