BCO1

Gene Symbol	BCO1
Entrez Gene	53630
Alt Symbol	BCDO, BCDO1, BCMO, BCMO1, BCO
Species	Human
Gene Type	protein-coding
Description	beta-carotene oxygenase 1
Other Description	beta,beta-carotene 15,15'-monooxygenase|beta-carotene 15, 15'-dioxygenase 1|beta-carotene 15,15'-monooxygenase 1|beta-carotene dioxygenase 1
Swissprots	A0AV48 Q9HAY6 Q9NVH5 A0AV50
Accessions	EAW95537 EAW95538 Q9HAY6 AF294900 AAG15380 AK001592 BAA91776 AK296011 BAG58782 BC022269 BC126210 AAI26211 BC126212 AAI26213 HQ258298 ADR83052 XM_011523109 XP_011521411 XM_011523110 XP_011521412 NM_017429 NP_059125
Function	Symmetrically cleaves beta-carotene into two molecules of retinal. The reaction proceeds in three stages, epoxidation of the 15,15'-double bond, hydration of the double bond leading to ring opening, and oxidative cleavage of the diol formed.
Tissue Specificity	Highly expressed in retinal pigment epithelium. Also expressed in kidney, testis, liver, brain, small intestine and colon. {ECO:0000269|PubMed:11401432}.
Top Pathways	Retinol metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BCO1 overexpression lysate - LY413785 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

BCMO1 293 Cell Lysate - 406631 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

BCMO1 Overexpression Lysate (Native) - NBP2-06984 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

BCMO1 Over-expression Lysate Product - GWB-3352AB from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Panoply™ Human BCMO1 Knockdown Stable Cell Line - CSC-DC001390 from Creative biogene Category Cell Line Species Human

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