BCO1

Gene Symbol	BCO1
Entrez Gene	53630
Alt Symbol	BCDO, BCDO1, BCMO, BCMO1, BCO
Species	Human
Gene Type	protein-coding
Description	beta-carotene oxygenase 1
Other Description	beta,beta-carotene 15,15'-monooxygenase|beta-carotene 15, 15'-dioxygenase 1|beta-carotene 15,15'-monooxygenase 1|beta-carotene dioxygenase 1
Swissprots	A0AV48 Q9HAY6 Q9NVH5 A0AV50
Accessions	EAW95537 EAW95538 Q9HAY6 AF294900 AAG15380 AK001592 BAA91776 AK296011 BAG58782 BC022269 BC126210 AAI26211 BC126212 AAI26213 HQ258298 ADR83052 XM_011523109 XP_011521411 XM_011523110 XP_011521412 NM_017429 NP_059125
Function	Symmetrically cleaves beta-carotene into two molecules of retinal. The reaction proceeds in three stages, epoxidation of the 15,15'-double bond, hydration of the double bond leading to ring opening, and oxidative cleavage of the diol formed.
Tissue Specificity	Highly expressed in retinal pigment epithelium. Also expressed in kidney, testis, liver, brain, small intestine and colon. {ECO:0000269|PubMed:11401432}.
Top Pathways	Retinol metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BCMO1 protein fragment - ab162695 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BCO1 / BCMO1 Antibody Blocking Peptide - LS-E237 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BCO1 / BCMO1 Antibody Blocking Peptide - LS-E23388 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BCMO1 Protein - H00053630-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

BCMO1-Antibody-Center-Blocking-Peptide - BP10472c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BCMO1 - H00053630-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

BCMO1 - H00053630-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

BCMO1 fusion protein - Ag19732 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

BCMO1 fusion protein - ag19519 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human BCMO1, His-tagged - BCMO1-10192H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Beta-Carotene-15,15'-Monooxygenase 1 (bCMO1) - RPE246Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Beta-Carotene-15,15'-Monooxygenase 1 (bCMO1) - RPE246Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Beta,beta-carotene 15,15'-monooxygenase(BCMO1) - CSB-YP864015HU CSB-EP864015HU CSB-BP864015HU CSB-MP864015HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BCMO1 - TP323790 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

BCMO1 Protein - NBP1-91698PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

BCMO1 Peptide, Human - M34GP01390H from Creative Peptides Category Peptide Source Synthetic. Species Human

BCO1 Recombinant Protein (OPCD01613) - OPCD01613 from Aviva Systems Biology Category Protein Source E.coli Species Human

BCMO1, Recombinant Protein - MBS8248599 from MyBioSource Category Protein Prices $255.00, $635.00, $2,370.00 Sizes 10 µg, 50 µg, 500 µg Source Human cells Species Human

Beta,beta-carotene 15,15'-monooxygenase (BCMO1), Recombinant Protein - MBS1431564 from MyBioSource Category Protein Prices $1,340.00, $1,340.00, $1,560.00, $1,560.00, $2,220.00, $2,220.00, $2,685.00, $2,685.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Beta-Carotene-15,15'-Monooxygenase 1, Recombinant Protein - MBS2033403 from MyBioSource Category Protein Prices $185.00, $385.00, $595.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli

Human BCMO1 protein - orb391289 from Biorbyt Category Protein Species Human

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