Gabarapl2

Gene Symbol	Gabarapl2
Entrez Gene	93739
Alt Symbol	0610012F20Rik, 2900019O08Rik, AI173605, GATE-16, Gef2
Species	Mouse
Gene Type	protein-coding
Description	gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
Other Description	GABA(A) receptor-associated protein like 2|GABA(A) receptor-associated protein-like 2|gamma-aminobutyric acid (GABA-A) receptor-associated protein-like 2|gamma-aminobutyric acid receptor-associated protein-like 2|ganglioside expression factor 2|golgi-associated ATPase enhancer of 16 kDa
Swissprots	P60521
Accessions	EDL11519 P60521 AF190644 AAK16238 AI845404 AK002596 BAB22217 AK013563 AK049819 BAC33933 AK134873 AK184306 BC026798 AAH26798 BC081436 AAH81436 NM_026693 NP_080969
Function	Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000250}.
Subcellular Location	Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, autophagosome {ECO:0000250}.
Tissue Specificity	Ubiquitous. A high level expression is seen in brain, thymus, lung, heart, liver and kidney. {ECO:0000269|PubMed:11414770}.
Top Pathways	GABAergic synapse, Regulation of autophagy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse GABARAPL2 Gene cDNA Clone - orb171706 from Biorbyt Prices $264.00 Sizes 10 μg Species Mouse

Mouse Gabarapl2 ORF Clone(NM_026693.5) - CDCR259130 from Creative Biomart Species Mouse Accession NM_026693.5

Mouse Gabarapl2 ORF Clone(NM_026693.5) - CDCR259131 from Creative Biomart Species Mouse Accession NM_026693.5

Mouse Gabarapl2 ORF clone - CDCL110137 from Creative Biomart Species Mouse Accession NM_026693

Mouse Gabarapl2 ORF clone - CDCL110138 from Creative Biomart Species Mouse Accession NM_026693

Mouse Gabarapl2 ORF Clone(NM_026693.5) - CDCL164194 from Creative Biomart Species Mouse Accession NM_026693.5

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone in cloning vector - MG51323-U from Sino Biological Species Mouse

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - MG51323-ACG from Sino Biological Species Mouse

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone expression plasmid - MG51323-UT from Sino Biological Species Mouse

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone expression plasmid, C-HA tag - MG51323-CY from Sino Biological Species Mouse

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - MG51323-ACR from Sino Biological Species Mouse

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone expression plasmid, N-Flag tag - MG51323-NF from Sino Biological Species Mouse

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone expression plasmid, C-His tag - MG51323-CH from Sino Biological Species Mouse

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone expression plasmid, N-HA tag - MG51323-NY from Sino Biological Species Mouse

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone expression plasmid, N-His tag - MG51323-NH from Sino Biological Species Mouse

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone expression plasmid, C-Flag tag - MG51323-CF from Sino Biological Species Mouse

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone expression plasmid, N-Myc tag - MG51323-NM from Sino Biological Species Mouse

Mouse GATE-16 / GABARAPL2 Gene ORF cDNA clone expression plasmid, C-Myc tag - MG51323-CM from Sino Biological Species Mouse

Mouse Gabarapl2 ORF Clone(NM_026693.5) - CDCR259130 from Creative biogene Species Mouse

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