Gabarapl2

Gene Symbol Gabarapl2
Entrez Gene 93739
Alt Symbol 0610012F20Rik, 2900019O08Rik, AI173605, GATE-16, Gef2
Species Mouse
Gene Type protein-coding
Description gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
Other Description GABA(A) receptor-associated protein like 2|GABA(A) receptor-associated protein-like 2|gamma-aminobutyric acid (GABA-A) receptor-associated protein-like 2|gamma-aminobutyric acid receptor-associated protein-like 2|ganglioside expression factor 2|golgi-associated ATPase enhancer of 16 kDa
Swissprots P60521
Accessions EDL11519 P60521 AF190644 AAK16238 AI845404 AK002596 BAB22217 AK013563 AK049819 BAC33933 AK134873 AK184306 BC026798 AAH26798 BC081436 AAH81436 NM_026693 NP_080969
Function Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000250}.
Subcellular Location Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, autophagosome {ECO:0000250}.
Tissue Specificity Ubiquitous. A high level expression is seen in brain, thymus, lung, heart, liver and kidney. {ECO:0000269|PubMed:11414770}.
Top Pathways GABAergic synapse, Regulation of autophagy

Recombinant Mouse Gamma-aminobutyric acid receptor-associated protein-like 2(Gabarapl2) - CSB-YP009132MO CSB-EP009132MO CSB-BP009132MO CSB-MP009132MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse GABARAPL2 Protein - GABARAPL2-6140M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

Gamma-aminobutyric acid receptor-associated protein-like 2 (Gabarapl2), Recombinant Protein - MBS968402 from MyBioSource

Category Protein
Prices $850.00, $850.00, $1,075.00, $1,075.00, $1,230.00, $1,230.00, $1,685.00, $1,685.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse
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