Gene Symbol | BPNT1 |
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Entrez Gene | 10380 |
Alt Symbol | HEL20, PIP |
Species | Human |
Gene Type | protein-coding |
Description | 3'(2'), 5'-bisphosphate nucleotidase 1 |
Other Description | 3'(2'),5'-bisphosphate nucleotidase 1|BPntase|PAP-inositol 1,4-phosphatase|PAP-inositol-1,4-phosphatase|bisphosphate 3'-nucleotidase 1|epididymis luminal protein 20 |
Swissprots | Q9UGJ3 A8K7C8 O95861 Q8WVL5 B4DUS9 D3DTA9 B4DPS5 |
Accessions | EAW93306 EAW93307 EAW93308 O95861 AF125042 AAD17329 AJ249339 CAB65115 AK021941 AK291943 BAF84632 AK298476 BAG60687 AK300777 BAG62441 AK315962 BAH14333 BC017801 AAH17801 BG114910 BG428446 DC368603 EU794594 ACJ13648 XM_005272998 XP_005273055 XM_005272999 XP_005273056 XM_005273000 XP_005273057 XM_005273004 XP_005273061 XM_005273005 XP_005273062 XM_006711114 XP_006711177 XM_011509063 XP_011507365 XM_011509064 XP_011507366 XM_011509065 XP_011507367 NM_001286149 NP_001273078 NM_001286150 NP_001273079 NM_001286151 NP_001273080 NM_006085 NP_006076 |
Function | Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Has 1000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4- trisphosphate (Ins(1,3,4)P3), but does not hydrolyze Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6. {ECO:0000269|PubMed:10224133}. |
Tissue Specificity | Highly expressed in kidney, liver, pancreas and heart. Detected at lower levels in brain, placenta, lung and skeletal muscle. {ECO:0000269|PubMed:10224133}. |
Top Pathways | Sulfur metabolism |
BPNT1 (C-12) - sc-393185 from Santa Cruz Biotechnology
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BPNT1 (P-14) - sc-103415 from Santa Cruz Biotechnology
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BPNT1 (31) - sc-136496 from Santa Cruz Biotechnology
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BPNT1 (N-15) - sc-103414 from Santa Cruz Biotechnology
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Anti-BPNT1 antibody - ab56679 from Abcam
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Anti-BPNT1 antibody - ab129694 from Abcam
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Anti-BPNT1 antibody - ab172551 from Abcam
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Anti-BPNT1 Antibody (aa277-305, AP) - LS-C252656 from LifeSpan Bioscience
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Anti-BPNT1 Antibody (aa277-305, APC) - LS-C252657 from LifeSpan Bioscience
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Anti-BPNT1 Antibody (aa277-305, Biotin) - LS-C252658 from LifeSpan Bioscience
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Anti-BPNT1 Antibody (aa277-305, FITC) - LS-C252659 from LifeSpan Bioscience
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Anti-BPNT1 Antibody (aa277-305, Azide-free, HRP) - LS-C252660 from LifeSpan Bioscience
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Anti-BPNT1 Antibody (aa277-305, PE) - LS-C252661 from LifeSpan Bioscience
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Anti-BPNT1 Antibody (aa276-305) - LS-C319866 from LifeSpan Bioscience
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Anti-BPNT1 Antibody (aa35-84) - LS-C102805 from LifeSpan Bioscience
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Anti-BPNT1 Antibody (aa253-267) - LS-C54583 from LifeSpan Bioscience
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Anti-BPNT1 Antibody (aa277-305) - LS-C156850 from LifeSpan Bioscience
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Anti-BPNT1 Antibody (clone 2E1) - LS-C133641 from LifeSpan Bioscience
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BPNT1 Antibody (2E1) - H00010380-M01 from Novus Biologicals
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BPNT1 Antibody - NBP2-14359 from Novus Biologicals
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PIP Antibody - NBP1-83386 from Novus Biologicals
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BPNT1 Antibody - NBP1-32152 from Novus Biologicals
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PIP Antibody (PIP2 2C11) - NB100-2751 from Novus Biologicals
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PIP Antibody (23A3) - NB100-1898 from Novus Biologicals
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BPNT1 Antibody - NB100-68164 from Novus Biologicals
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