| Gene Symbol |
BPNT1
|
| Entrez Gene |
10380
|
| Alt Symbol |
HEL20, PIP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
3'(2'), 5'-bisphosphate nucleotidase 1
|
| Other Description |
3'(2'),5'-bisphosphate nucleotidase 1|BPntase|PAP-inositol 1,4-phosphatase|PAP-inositol-1,4-phosphatase|bisphosphate 3'-nucleotidase 1|epididymis luminal protein 20
|
| Swissprots |
Q9UGJ3 A8K7C8 O95861 Q8WVL5 B4DUS9 D3DTA9 B4DPS5
|
| Accessions |
EAW93306 EAW93307 EAW93308 O95861 AF125042 AAD17329 AJ249339 CAB65115 AK021941 AK291943 BAF84632 AK298476 BAG60687 AK300777 BAG62441 AK315962 BAH14333 BC017801 AAH17801 BG114910 BG428446 DC368603 EU794594 ACJ13648 XM_005272998 XP_005273055 XM_005272999 XP_005273056 XM_005273000 XP_005273057 XM_005273004 XP_005273061 XM_005273005 XP_005273062 XM_006711114 XP_006711177 XM_011509063 XP_011507365 XM_011509064 XP_011507366 XM_011509065 XP_011507367 NM_001286149 NP_001273078 NM_001286150 NP_001273079 NM_001286151 NP_001273080 NM_006085 NP_006076
|
| Function |
Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Has 1000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4- trisphosphate (Ins(1,3,4)P3), but does not hydrolyze Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6. {ECO:0000269|PubMed:10224133}.
|
| Tissue Specificity |
Highly expressed in kidney, liver, pancreas and heart. Detected at lower levels in brain, placenta, lung and skeletal muscle. {ECO:0000269|PubMed:10224133}.
|
| Top Pathways |
Sulfur metabolism
|