| Gene Symbol | ITGAE |
|---|---|
| Entrez Gene | 3682 |
| Alt Symbol | CD103, HUMINAE |
| Species | Human |
| Gene Type | protein-coding |
| Description | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
| Other Description | HML-1 antigen|antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide|integrin alpha-E|integrin alpha-IEL|mucosal lymphocyte 1 antigen |
| Swissprots | Q9NZU9 P38570 Q17RS6 |
| Accessions | AAF43107 EAW90480 P38570 AF289864 AK097567 BC113436 AAI13437 BC117207 AAI17208 CD368046 HQ258689 ADR83440 L25851 AAB59359 XM_011523823 XP_011522125 XM_011523824 XP_011522126 XM_011523825 XP_011522127 XM_011523826 XP_011522128 XM_011523827 XP_011522129 XM_011523828 XP_011522130 XR_934020 NM_002208 NP_002199 |
| Function | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. |
| Top Pathways | Regulation of actin cytoskeleton |