| Gene Symbol |
ITGAE
|
| Entrez Gene |
3682
|
| Alt Symbol |
CD103, HUMINAE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
| Other Description |
HML-1 antigen|antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide|integrin alpha-E|integrin alpha-IEL|mucosal lymphocyte 1 antigen
|
| Swissprots |
Q9NZU9 P38570 Q17RS6
|
| Accessions |
AAF43107 EAW90480 P38570 AF289864 AK097567 BC113436 AAI13437 BC117207 AAI17208 CD368046 HQ258689 ADR83440 L25851 AAB59359 XM_011523823 XP_011522125 XM_011523824 XP_011522126 XM_011523825 XP_011522127 XM_011523826 XP_011522128 XM_011523827 XP_011522129 XM_011523828 XP_011522130 XR_934020 NM_002208 NP_002199
|
| Function |
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
|
| Top Pathways |
Regulation of actin cytoskeleton
|