Gene Symbol | ITGAE |
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Entrez Gene | 3682 |
Alt Symbol | CD103, HUMINAE |
Species | Human |
Gene Type | protein-coding |
Description | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
Other Description | HML-1 antigen|antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide|integrin alpha-E|integrin alpha-IEL|mucosal lymphocyte 1 antigen |
Swissprots | Q9NZU9 P38570 Q17RS6 |
Accessions | AAF43107 EAW90480 P38570 AF289864 AK097567 BC113436 AAI13437 BC117207 AAI17208 CD368046 HQ258689 ADR83440 L25851 AAB59359 XM_011523823 XP_011522125 XM_011523824 XP_011522126 XM_011523825 XP_011522127 XM_011523826 XP_011522128 XM_011523827 XP_011522129 XM_011523828 XP_011522130 XR_934020 NM_002208 NP_002199 |
Function | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. |
Top Pathways | Regulation of actin cytoskeleton |
Integrin αE CRISPR/Cas9 KO Plasmid (h) - sc-404333 from Santa Cruz Biotechnology
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Integrin αE HDR Plasmid (h) - sc-404333-HDR from Santa Cruz Biotechnology
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Integrin αE Double Nickase Plasmid (h) - sc-404333-NIC from Santa Cruz Biotechnology
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Integrin αE Double Nickase Plasmid (h2) - sc-404333-NIC-2 from Santa Cruz Biotechnology
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Integrin αE CRISPR Activation Plasmid (h) - sc-404333-ACT from Santa Cruz Biotechnology
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Integrin αE CRISPR Activation Plasmid (h2) - sc-404333-ACT-2 from Santa Cruz Biotechnology
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Integrin αE Lentiviral Activation Particles (h) - sc-404333-LAC from Santa Cruz Biotechnology
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Integrin αE Lentiviral Activation Particles (h2) - sc-404333-LAC-2 from Santa Cruz Biotechnology
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Integrin αE siRNA (h) - sc-35690 from Santa Cruz Biotechnology
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Integrin αE shRNA Plasmid (h) - sc-35690-SH from Santa Cruz Biotechnology
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Integrin αE shRNA (h) Lentiviral Particles - sc-35690-V from Santa Cruz Biotechnology
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Integrin alpha E/CD103 RNAi - H00003682-R01 from Novus Biologicals
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MISSION® esiRNA - EHU015041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10813 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10813 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01469 from Sigma-Aldrich
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ITGAE siRNA (Human) - CRH2472 from Cohesion Biosciences
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ITGAE - MBS8234393 from MyBioSource
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shRNA set against Human ITGAE (NM_002208.4) - SHH321281 from Creative biogene
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shRNA set against Human ITGAE(NM_002208.4) - SHL181776 from Creative biogene
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ITGAE shRNA Plasmid (Human) - CHH2472 from Cohesion Biosciences
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ITGAE miRNA 3'UTR clone - MiUTR1H-05028 from Creative biogene
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