| Gene Symbol |
LDLRAD3
|
| Entrez Gene |
143458
|
| Alt Symbol |
LRAD3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
low density lipoprotein receptor class A domain containing 3
|
| Other Description |
low-density lipoprotein receptor class A domain-containing protein 3
|
| Swissprots |
Q8NBJ0 B7Z1U3 Q86YD5 B9EG81
|
| Accessions |
CAI72191 EAW68125 EAW68126 EAW68127 Q86YD5 AK075546 BAC11689 AK293930 BAH11629 AK299186 BAH12964 BC042754 AAH42754 BC136286 AAI36287 BC143823 BC143824 AAI43825 BY997532 CK904050 NM_001304263 NP_001291192 NM_001304264 NP_001291193 NM_174902 NP_777562
|
| Function |
May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed at high levels in brain, lung, skeletal muscle, and pancreas. Expressed at moderate levels in heart, placenta, and kidney but not detected in the liver. {ECO:0000269|PubMed:21795536}.
|