Gene Symbol | LDLRAD3 |
---|---|
Entrez Gene | 143458 |
Alt Symbol | LRAD3 |
Species | Human |
Gene Type | protein-coding |
Description | low density lipoprotein receptor class A domain containing 3 |
Other Description | low-density lipoprotein receptor class A domain-containing protein 3 |
Swissprots | Q8NBJ0 B7Z1U3 Q86YD5 B9EG81 |
Accessions | CAI72191 EAW68125 EAW68126 EAW68127 Q86YD5 AK075546 BAC11689 AK293930 BAH11629 AK299186 BAH12964 BC042754 AAH42754 BC136286 AAI36287 BC143823 BC143824 AAI43825 BY997532 CK904050 NM_001304263 NP_001291192 NM_001304264 NP_001291193 NM_174902 NP_777562 |
Function | May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed at high levels in brain, lung, skeletal muscle, and pancreas. Expressed at moderate levels in heart, placenta, and kidney but not detected in the liver. {ECO:0000269|PubMed:21795536}. |