Gene Symbol | LDLRAD3 |
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Entrez Gene | 143458 |
Alt Symbol | LRAD3 |
Species | Human |
Gene Type | protein-coding |
Description | low density lipoprotein receptor class A domain containing 3 |
Other Description | low-density lipoprotein receptor class A domain-containing protein 3 |
Swissprots | Q8NBJ0 B7Z1U3 Q86YD5 B9EG81 |
Accessions | CAI72191 EAW68125 EAW68126 EAW68127 Q86YD5 AK075546 BAC11689 AK293930 BAH11629 AK299186 BAH12964 BC042754 AAH42754 BC136286 AAI36287 BC143823 BC143824 AAI43825 BY997532 CK904050 NM_001304263 NP_001291192 NM_001304264 NP_001291193 NM_174902 NP_777562 |
Function | May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed at high levels in brain, lung, skeletal muscle, and pancreas. Expressed at moderate levels in heart, placenta, and kidney but not detected in the liver. {ECO:0000269|PubMed:21795536}. |
LDLRAD3 CRISPR/Cas9 KO Plasmid (h) - sc-414519 from Santa Cruz Biotechnology
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LDLRAD3 HDR Plasmid (h) - sc-414519-HDR from Santa Cruz Biotechnology
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LDLRAD3 Double Nickase Plasmid (h) - sc-414519-NIC from Santa Cruz Biotechnology
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LDLRAD3 Double Nickase Plasmid (h2) - sc-414519-NIC-2 from Santa Cruz Biotechnology
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LDLRAD3 CRISPR Activation Plasmid (h) - sc-414519-ACT from Santa Cruz Biotechnology
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LDLRAD3 CRISPR Activation Plasmid (h2) - sc-414519-ACT-2 from Santa Cruz Biotechnology
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LDLRAD3 Lentiviral Activation Particles (h) - sc-414519-LAC from Santa Cruz Biotechnology
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LDLRAD3 Lentiviral Activation Particles (h2) - sc-414519-LAC-2 from Santa Cruz Biotechnology
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LDLRAD3 siRNA (h) - sc-96574 from Santa Cruz Biotechnology
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LDLRAD3 shRNA Plasmid (h) - sc-96574-SH from Santa Cruz Biotechnology
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LDLRAD3 shRNA (h) Lentiviral Particles - sc-96574-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU035091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11628 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11628 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12767 from Sigma-Aldrich
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LDLRAD3 siRNA (Human) - CRJ5372 from Cohesion Biosciences
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LDLRAD3 RNAi - H00143458-R02 from Novus Biologicals
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shRNA set against Human LDLRAD3 (NM_174902.2) - SHH329371 from Creative biogene
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shRNA set against Human LDLRAD3(NM_174902.2) - SHH145631 from Creative biogene
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Human LDLRAD3 siRNA - orb275873 from Biorbyt
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LDLRAD3 shRNA Plasmid (Human) - CHJ5372 from Cohesion Biosciences
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LDLRAD3 miRNA 3'UTR clone - MiUTR1H-05624 from Creative biogene
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