Gene Symbol | RIC1 |
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Entrez Gene | 57589 |
Alt Symbol | CIP150, KIAA1432, bA207C16.1 |
Species | Human |
Gene Type | protein-coding |
Description | RAB6A GEF complex partner 1 |
Other Description | RAB6A-GEF complex partner protein 1|connexin 43-interacting protein 150 kDa|connexin-43-interacting protein of 150 kDa|protein RIC1 homolog |
Swissprots | B7ZM67 Q4VXJ9 G5E932 B2RN24 Q4VXJ8 Q9H0A5 Q76MT5 Q8TEH4 Q4ADV7 Q9H9S1 Q8N6E0 |
Accessions | EAW58759 EAW58760 EAW58761 Q4ADV7 AA250979 AB037853 BAA92670 AB205401 BAE16982 AK022642 BAB14150 AK074150 BAB84976 AK124394 AL136875 CAB66809 BC023535 BC030576 AAH30576 BC041044 BC136616 AAI36617 BC144296 AAI44297 R44399 XM_005251523 XP_005251580 XM_011517967 XP_011516269 XM_011517968 XP_011516270 XR_428426 NM_001135920 NP_001129392 NM_001206557 NP_001193486 NM_020829 NP_065880 |
Function | The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1- RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1. {ECO:0000269|PubMed:16112082, ECO:0000269|PubMed:23091056}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:23091056}. Membrane {ECO:0000269|PubMed:23091056}; Single-pass membrane protein {ECO:0000255}. |
Tissue Specificity | Present in kidney and various cell lines (at protein level). Widely expressed at low level. {ECO:0000269|PubMed:10718198, ECO:0000269|PubMed:16112082}. |
KIAA1432 (N-15) - sc-162987 from Santa Cruz Biotechnology
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Anti-KIAA1432 antibody - ab188302 from Abcam
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Anti-KIAA1432 antibody produced in rabbit - HPA051578 from Sigma-Aldrich
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KIAA1432 Antibody - NBP2-49012 from Novus Biologicals
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RIC1 Antibody,Biotin conjugated - CSB-PA671121LD01HU from Cusabio
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RIC1 Antibody,FITC conjugated - CSB-PA671121LC01HU from Cusabio
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RIC1 Antibody,HRP conjugated - CSB-PA671121LB01HU from Cusabio
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RIC1 Antibody - CSB-PA671121LA01HU from Cusabio
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RIC1, Polyclonal Antibody - MBS7043929 from MyBioSource
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RIC1, Polyclonal Antibody - MBS7046305 from MyBioSource
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RIC1, Polyclonal Antibody - MBS7045351 from MyBioSource
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RIC1, Polyclonal Antibody - MBS7045877 from MyBioSource
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RIC1 antibody (HRP) - orb45010 from Biorbyt
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RIC1 antibody (FITC) - orb45011 from Biorbyt
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RIC1 antibody (Biotin) - orb45012 from Biorbyt
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