RIC1

Gene Symbol RIC1
Entrez Gene 57589
Alt Symbol CIP150, KIAA1432, bA207C16.1
Species Human
Gene Type protein-coding
Description RAB6A GEF complex partner 1
Other Description RAB6A-GEF complex partner protein 1|connexin 43-interacting protein 150 kDa|connexin-43-interacting protein of 150 kDa|protein RIC1 homolog
Swissprots B7ZM67 Q4VXJ9 G5E932 B2RN24 Q4VXJ8 Q9H0A5 Q76MT5 Q8TEH4 Q4ADV7 Q9H9S1 Q8N6E0
Accessions EAW58759 EAW58760 EAW58761 Q4ADV7 AA250979 AB037853 BAA92670 AB205401 BAE16982 AK022642 BAB14150 AK074150 BAB84976 AK124394 AL136875 CAB66809 BC023535 BC030576 AAH30576 BC041044 BC136616 AAI36617 BC144296 AAI44297 R44399 XM_005251523 XP_005251580 XM_011517967 XP_011516269 XM_011517968 XP_011516270 XR_428426 NM_001135920 NP_001129392 NM_001206557 NP_001193486 NM_020829 NP_065880
Function The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1- RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1. {ECO:0000269|PubMed:16112082, ECO:0000269|PubMed:23091056}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:23091056}. Membrane {ECO:0000269|PubMed:23091056}; Single-pass membrane protein {ECO:0000255}.
Tissue Specificity Present in kidney and various cell lines (at protein level). Widely expressed at low level. {ECO:0000269|PubMed:10718198, ECO:0000269|PubMed:16112082}.

KIAA1432 CRISPR/Cas9 KO Plasmid (h) - sc-417074 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA1432 HDR Plasmid (h) - sc-417074-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA1432 Double Nickase Plasmid (h) - sc-417074-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA1432 Double Nickase Plasmid (h2) - sc-417074-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA1432 CRISPR Activation Plasmid (h) - sc-417074-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA1432 CRISPR Activation Plasmid (h2) - sc-417074-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA1432 Lentiviral Activation Particles (h) - sc-417074-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA1432 Lentiviral Activation Particles (h2) - sc-417074-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA1432 siRNA (h) - sc-92643 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KIAA1432 shRNA Plasmid (h) - sc-92643-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KIAA1432 shRNA (h) Lentiviral Particles - sc-92643-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU065791 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11131 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11131 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

KIAA1432 siRNA (Human) - CRJ1562 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KIAA1432 (NM_020829.3) - SHH324779 from Creative biogene

Category siRNA
Species Reactivities Human

KIAA1432 shRNA Plasmid (Human) - CHJ1562 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KIAA1432 miRNA 3'UTR clone - MiUTR3H-11181 from Creative biogene

Species Reactivities Human
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