IKZF3

Gene Symbol IKZF3
Entrez Gene 22806
Alt Symbol AIO, AIOLOS, ZNFN1A3
Species Human
Gene Type protein-coding
Description IKAROS family zinc finger 3 (Aiolos)
Other Description zinc finger DNA binding protein Aiolos|zinc finger protein Aiolos|zinc finger protein, subfamily 1A, 3 (Aiolos)
Swissprots Q69BM1 Q8WWR1 Q8WWQ9 Q69BM5 B4DVV5 Q69BL8 Q69BL7 Q69BL6 Q69BL9 Q69BM0 Q8N574 Q8WWR0 Q69BM2 Q9UKT9 Q8WWR2 Q69BM3 Q8WWR3
Accessions EAW60604 EAW60605 EAW60606 EAW60607 EAW60608 EAW60609 Q9UKT9 AF086054 AF129512 AAF13493 AI866838 AJ292565 CAC80427 AJ292566 CAC80428 AJ292567 CAC80429 AJ292568 CAC80430 AJ292569 CAC80431 AK128436 AK301250 BAG62817 AK303495 BAG64529 AY377973 AAR84584 AY377975 AAR84586 AY377976 AAR84587 AY377977 AAR84588 AY377978 AAR84589 AY377979 AAR84590 AY377980 AAR84591 AY377981 AAR84592 AY377982 AAR84593 BC032707 AAH32707 EU446776 ABZ92305 HG509027 JF432186 ADZ15403 NM_001257408 NP_001244337 NM_001257409 NP_001244338 NM_001257410 NP_001244339 NM_001257411 NP_001244340 NM_001257412 NP_001244341 NM_001257413 NP_001244342 NM_001257414 NP_001244343 NM_001284514 NP_001271443 NM_001284515 NP_001271444 NM_001284516 NP_001271445 NM_012481 NP_036613 NM_183228 NP_899051 NM_183229 NP_899052 NM_183230 NP_899053 NM_183231 NP_899054 NM_183232 NP_899055
Function Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2- dependent manner. {ECO:0000269|PubMed:10369681}.
Subcellular Location Nucleus. Cytoplasm.
Tissue Specificity Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus. {ECO:0000269|PubMed:17646674}.

Aiolos CRISPR/Cas9 KO Plasmid (h) - sc-400764 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Aiolos HDR Plasmid (h) - sc-400764-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Aiolos Double Nickase Plasmid (h) - sc-400764-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Aiolos Double Nickase Plasmid (h2) - sc-400764-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Aiolos CRISPR Activation Plasmid (h) - sc-400764-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Aiolos CRISPR Activation Plasmid (h2) - sc-400764-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Aiolos Lentiviral Activation Particles (h) - sc-400764-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Aiolos Lentiviral Activation Particles (h2) - sc-400764-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Aiolos siRNA (h) - sc-93817 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Aiolos shRNA Plasmid (h) - sc-93817-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Aiolos shRNA (h) Lentiviral Particles - sc-93817-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Aiolos/IKZF3 RNAi - H00022806-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Aiolos/IKZF3 RNAi - H00022806-R05 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

Aiolos/IKZF3 RNAi - H00022806-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Aiolos/IKZF3 RNAi - H00022806-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Aiolos/IKZF3 RNAi - H00022806-R06 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

Aiolos/IKZF3 RNAi - H00022806-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU078951 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10558 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10558 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06562 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06562

IKZF3 siRNA (Human) - CRH7783 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IKZF3 - MBS8223197 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Aiolos CRISPR/Cas9 KO Plasmid (h2) - sc-400764-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Aiolos HDR Plasmid (h2) - sc-400764-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human
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