CHSY1

Gene Symbol	CHSY1
Entrez Gene	22856
Alt Symbol	CHSY, CSS1, ChSy-1, TPBS
Species	Human
Gene Type	protein-coding
Description	chondroitin sulfate synthase 1
Other Description	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1|N-acetylgalactosaminyltransferase II|carbohydrate synthase 1|chondroitin glucuronyltransferase 1|chondroitin glucuronyltransferase II|chondroitin synthase 1|glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1
Swissprots	Q9Y2J5 Q86X52 Q7LFU5 Q6UX38
Accessions	EAX02292 Q86X52 AB023207 BAA76834 AB071402 BAB64936 AK075096 AK296943 BAG59492 AL137409 AY358529 AAQ88893 BC046247 AAH46247 BQ007796 XM_006720435 XP_006720498 XM_011521364 XP_011519666 XM_011521365 XP_011519667 NM_014918 NP_055733
Function	Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling. {ECO:0000269|PubMed:11514575, ECO:0000269|PubMed:21129727}.
Subcellular Location	Golgi apparatus, Golgi stack membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Secreted.
Tissue Specificity	Ubiquitous, with the highest levels in placenta. Detected at low levels in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, adrenal gland, mammary gland, stomach, small intestine, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:11514575, ECO:0000269|PubMed:12907687}.
Top Pathways	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CHSY1 (D-20) - sc-50543 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

CHSY1 (H-300) - sc-292185 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

CHSY1 (N-13) - sc-50545 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-CHSY1 antibody - ab116116 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-CHSY1 antibody - ab136013 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CHSY1 Antibody (aa503-533, AP) - LS-C254833 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CHSY1 Antibody (aa503-533, APC) - LS-C254834 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CHSY1 Antibody (aa503-533, Biotin) - LS-C254835 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CHSY1 Antibody (aa341-390) - LS-C291310 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CHSY1 Antibody (aa503-533, Azide-free, HRP) - LS-C254836 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CHSY1 Antibody (aa503-533, PE) - LS-C254838 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CHSY1 Antibody (aa503-533, FITC) - LS-C254837 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CHSY1 Antibody (aa327-376) - LS-C291805 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CHSY1 Antibody (aa503-533) - LS-C320389 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CHSY1 Antibody (C-Terminus) - LS-C345653 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CHSY1 Antibody (aa503-533) - LS-C168767 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

CHSY1 Antibody - NBP2-15899 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

CHSY1 Antibody - NBP2-13838 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CHSY1 antibody produced in rabbit - SAB2700099 from Sigma-Aldrich Prices $326.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CHSY1 antibody produced in rabbit - HPA048902 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ANTI-CHSY1 (CENTER) antibody produced in rabbit - SAB1302516 from Sigma-Aldrich Prices $326.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

CHSS1 Antibody - C-terminal region (ARP73930_P050) - ARP73930_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

CHSY1-Antibody-Center - AP13586c from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

CHSY1 antibody [N2C1], Internal - GTX115638 from GeneTex Prices $119.00 Sizes 25 μl Host Rabbit Clonality Polyclonal

CHSY1 Antibody - middle region (OAAB09887) - OAAB09887 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

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