Gene Symbol | ZMAT3 |
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Entrez Gene | 64393 |
Alt Symbol | PAG608, WIG-1, WIG1 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger, matrin-type 3 |
Other Description | WIG-1/PAG608 protein|p53 target zinc finger protein|p53-activated gene 608 protein|zinc finger matrin-type protein 3|zinc finger protein WIG-1|zinc finger protein WIG1|zinc finger, matrin type 3 |
Swissprots | Q96A21 D3DNR1 Q9HA38 B3KVA6 |
Accessions | CAE91449 EAW78424 EAW78425 EAW78426 Q9HA38 AF355465 AAK83287 AK022358 BAB14020 AK056245 AK122768 BAG53718 AY037945 AAK71491 BC002896 AAH02896 BC036485 DA001239 HQ447424 ADQ31910 XM_005247706 XP_005247763 XM_011513073 XP_011511375 NM_022470 NP_071915 NM_152240 NP_689426 |
Function | Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. {ECO:0000269|PubMed:11571644}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11571644}. Nucleus, nucleolus {ECO:0000269|PubMed:11571644}. |
Tissue Specificity | Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine. {ECO:0000269|PubMed:11689294}. |
Top Pathways | p53 signaling pathway |
Wig-1 (C-1) - sc-398712 from Santa Cruz Biotechnology
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Wig-1 (M-20) - sc-8165 from Santa Cruz Biotechnology
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Wig-1 (V-16) - sc-8166 from Santa Cruz Biotechnology
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Wig-1 (Q-21) - sc-134151 from Santa Cruz Biotechnology
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Anti-PAG608 antibody - ab96285 from Abcam
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Anti-PAG608 antibody - ab191536 from Abcam
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Anti-PAG608 antibody - ab112529 from Abcam
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Anti-PAG608 antibody - ab67198 from Abcam
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Anti-ZMAT3 Antibody - LS-C340917 from LifeSpan Bioscience
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Anti-ZMAT3 Antibody (aa1-289) - LS-C178586 from LifeSpan Bioscience
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Anti-ZMAT3 Antibody (aa58-107) - LS-C81605 from LifeSpan Bioscience
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Anti-ZMAT3 Antibody - LS-C333703 from LifeSpan Bioscience
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PAG608 Antibody - NBP1-32543 from Novus Biologicals
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PAG608 Antibody - H00064393-B02 from Novus Biologicals
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PAG608 Antibody - H00064393-B01P from Novus Biologicals
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PAG608 Antibody - H00064393-B01 from Novus Biologicals
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PAG608 Polyclonal Antibody - bs-0942R from Bioss
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PAG608 Polyclonal Antibody - bs-0957R from Bioss
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PAG608 (3E4) Monoclonal Antibody - bsm-0957M from Bioss
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PAG608 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0942R-A350 from Bioss
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PAG608 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0942R-A488 from Bioss
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PAG608 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0942R-A555 from Bioss
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PAG608 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0942R-A647 from Bioss
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PAG608 Polyclonal Antibody, Cy3 Conjugated - bs-0942R-Cy3 from Bioss
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PAG608 Polyclonal Antibody, Cy5 Conjugated - bs-0942R-Cy5 from Bioss
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