Gene Symbol | ZMAT3 |
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Entrez Gene | 64393 |
Alt Symbol | PAG608, WIG-1, WIG1 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger, matrin-type 3 |
Other Description | WIG-1/PAG608 protein|p53 target zinc finger protein|p53-activated gene 608 protein|zinc finger matrin-type protein 3|zinc finger protein WIG-1|zinc finger protein WIG1|zinc finger, matrin type 3 |
Swissprots | Q96A21 D3DNR1 Q9HA38 B3KVA6 |
Accessions | CAE91449 EAW78424 EAW78425 EAW78426 Q9HA38 AF355465 AAK83287 AK022358 BAB14020 AK056245 AK122768 BAG53718 AY037945 AAK71491 BC002896 AAH02896 BC036485 DA001239 HQ447424 ADQ31910 XM_005247706 XP_005247763 XM_011513073 XP_011511375 NM_022470 NP_071915 NM_152240 NP_689426 |
Function | Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. {ECO:0000269|PubMed:11571644}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11571644}. Nucleus, nucleolus {ECO:0000269|PubMed:11571644}. |
Tissue Specificity | Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine. {ECO:0000269|PubMed:11689294}. |
Top Pathways | p53 signaling pathway |
Wig-1 CRISPR/Cas9 KO Plasmid (h) - sc-406638 from Santa Cruz Biotechnology
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Wig-1 HDR Plasmid (h) - sc-406638-HDR from Santa Cruz Biotechnology
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Wig-1 Double Nickase Plasmid (h) - sc-406638-NIC from Santa Cruz Biotechnology
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Wig-1 Double Nickase Plasmid (h2) - sc-406638-NIC-2 from Santa Cruz Biotechnology
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Wig-1 CRISPR Activation Plasmid (h) - sc-406638-ACT from Santa Cruz Biotechnology
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Wig-1 CRISPR Activation Plasmid (h2) - sc-406638-ACT-2 from Santa Cruz Biotechnology
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Wig-1 Lentiviral Activation Particles (h) - sc-406638-LAC from Santa Cruz Biotechnology
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Wig-1 Lentiviral Activation Particles (h2) - sc-406638-LAC-2 from Santa Cruz Biotechnology
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Wig-1 siRNA (h) - sc-106883 from Santa Cruz Biotechnology
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Wig-1 shRNA Plasmid (h) - sc-106883-SH from Santa Cruz Biotechnology
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Wig-1 shRNA (h) Lentiviral Particles - sc-106883-V from Santa Cruz Biotechnology
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PAG608 RNAi - H00064393-R02 from Novus Biologicals
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PAG608 RNAi - H00064393-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN23233 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23233 from Sigma-Aldrich
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ZMAT3 siRNA (Human) - CRJ2000 from Cohesion Biosciences
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ZMAT3 - MBS828609 from MyBioSource
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shRNA set against Human ZMAT3 (NM_022470.3) - SHH452812 from Creative biogene
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Human ZMAT3 siRNA - orb272501 from Biorbyt
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ZMAT3 shRNA Plasmid (Human) - CHJ2000 from Cohesion Biosciences
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