| Gene Symbol |
ZMAT3
|
| Entrez Gene |
64393
|
| Alt Symbol |
PAG608, WIG-1, WIG1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger, matrin-type 3
|
| Other Description |
WIG-1/PAG608 protein|p53 target zinc finger protein|p53-activated gene 608 protein|zinc finger matrin-type protein 3|zinc finger protein WIG-1|zinc finger protein WIG1|zinc finger, matrin type 3
|
| Swissprots |
Q96A21 D3DNR1 Q9HA38 B3KVA6
|
| Accessions |
CAE91449 EAW78424 EAW78425 EAW78426 Q9HA38 AF355465 AAK83287 AK022358 BAB14020 AK056245 AK122768 BAG53718 AY037945 AAK71491 BC002896 AAH02896 BC036485 DA001239 HQ447424 ADQ31910 XM_005247706 XP_005247763 XM_011513073 XP_011511375 NM_022470 NP_071915 NM_152240 NP_689426
|
| Function |
Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. {ECO:0000269|PubMed:11571644}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:11571644}. Nucleus, nucleolus {ECO:0000269|PubMed:11571644}.
|
| Tissue Specificity |
Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine. {ECO:0000269|PubMed:11689294}.
|
| Top Pathways |
p53 signaling pathway
|