PLEKHH2

Gene Symbol PLEKHH2
Entrez Gene 130271
Alt Symbol PLEKHH1L
Species Human
Gene Type protein-coding
Description pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Other Description pleckstrin homology domain-containing family H member 2
Swissprots Q8N3Q3 Q5JPJ6 Q8IVE3 Q6P4Q1
Accessions Q8IVE3 AB095948 BAC23124 AK124381 AK126308 AL832207 CAI46132 AL833400 CAD38637 AL833473 AL833546 AM392539 CAL37417 BC031914 BC063310 AAH63310 XM_011532539 XP_011530841 XR_244924 XR_426981 XR_939656 XR_939657 NM_172069 NP_742066
Function In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:22832517}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:22832517}. Cell membrane {ECO:0000269|PubMed:22832517}; Peripheral membrane protein {ECO:0000269|PubMed:22832517}; Cytoplasmic side {ECO:0000269|PubMed:22832517}. Cell projection, lamellipodium {ECO:0000269|PubMed:22832517}. Note=Localizes to foot process of podocytes. Localization to peripheral regions of lamellipodia seems to be dependent on PI3K.
Tissue Specificity Kidney. Reduced expression in patients with focal segmental glomerulosclerosis. {ECO:0000269|PubMed:22832517}.

Anti-PLEKHH2 antibody - ab81300 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PLEKHH2 antibody (ab81300) at 1 µg/ml + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PLEKHH2 Antibody (aa1043-1092) IHC-plus™ - LS-B3567 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PLEKHH2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3567 concentration 10 ug/ml.

Anti-PLEKHH2 Antibody (aa1049-1079, AP) - LS-C239116 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHH2 Antibody (aa1049-1079, Biotin) - LS-C239117 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHH2 Antibody (aa1049-1079, FITC) - LS-C239118 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHH2 Antibody (aa1049-1079, APC) - LS-C239115 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHH2 Antibody (aa1049-1079, PE) - LS-C239122 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHH2 Antibody (aa1049-1079, Azide-free, HRP) - LS-C248488 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHH2 Antibody (aa1057-1086) - LS-C324073 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHH2 Antibody (aa1049-1079) - LS-C163749 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PKHH2 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

PLEKHH2 Antibody - NBP1-70677 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PLEKHH2 Antibody [NBP1-70677] - Titration: 1 ug/ml Positive Control: Jurkat cell lysate.

PLEKHH2 Antibody - H00130271-B01P-50ug from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

ANTI-PKHH2 (C-TERM) antibody produced in rabbit - SAB1303168 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>PKHH2 (C-term): <B>Cat. No. SAB1303168</B>: PKHH2 in Human brain tissue with PKHH2 antibody (C-term) at 5 μg/mL.

Anti-PLEKHH2 antibody produced in rabbit - AV53218 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PLEKHH2: <B>Cat. No. AV53218</B>: Immunohistochemistry of PLEKHH2 in Human Heart tissue with PLEKHH2 antibody at 10 μg/mL.

PLEKHH2 antibody - C-terminal region (ARP53218_P050) - ARP53218_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PKHH2-Antibody-C-term - AP9773b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of PKHH2 Antibody (C-term) (Cat. #AP9773b) in Jurkat cell line lysates (35ug/lane). PKHH2 (arrow) was detected using the purified Pab.

PLEKHH2 Antibody - C-terminal region (OAAB06374) - OAAB06374 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

PLEKHH2 antibody - 70R-3507 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

PLEKHH2 (C-term) antibody - AP53317PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis in formalin fixed and paraffin embedded brain tissue reacted with PLEKHH2 Antibody (C-term) Cat.-No AP53317PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. This data demonstrates the use of the APKHH2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

PLEKHH2 antibody - H00130271-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

PLEKHH2 Antibody - 26-762 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Antibody used in IHC on Human Heart.

PLEKHH2 antibody - 14204-1-AP from Proteintech Group

Prices $279.00
Sizes con: 26 μg/150μl
Host Rabbit
Clonality Polyclonal
Jurkat cells were subjected to SDS PAGE followed by western blot with 14204-1-AP( PLEKHH2 Antibody) at dilution of 1:300

PLEKHH2 Antibody - GWB-MS976D from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PLEKHH2 monoclonal antibody - DCABH-16460 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

PLEKHH2 Polyclonal Antibody - PA5-26776 from Thermo Fisher Scientific

Prices $349.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis in formalin-fixed, paraffin-embedded brain tissue using a PKHH2 polyclonal antibody (Product ## PA5-26776), followed by HRP-conjugated secondary antibody and DAB staining.
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