UGT1A3

Gene Symbol UGT1A3
Entrez Gene 54659
Alt Symbol UDPGT, UDPGT 1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C
Species Human
Gene Type protein-coding
Description UDP glucuronosyltransferase 1 family, polypeptide A3
Other Description UDP glycosyltransferase 1 family, polypeptide A3|UDP-glucuronosyltransferase 1-3|UDP-glucuronosyltransferase 1-C|UDP-glucuronosyltransferase 1A3|UGT1*3
Swissprots B8K287 P35503
Accessions AAA92020 AAG30423 AAL73500 AAL73501 AAL73502 AAT94066 AAY32612 AAY32613 AAY32614 AAY32615 AAY32616 AAY32617 AAY32618 AAY32619 AAY32620 AAY32621 AAY32622 AAY32623 AAY32624 AAY32625 ABD60346 ABD60347 BAD12517 BAD12518 BAD12519 BAD12520 EAW71060 P35503 AY435138 AAR95639 BC166641 AAI66641 DQ364248 ABC96772 NM_019093 NP_061966
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1. {ECO:0000269|PubMed:18674515}.
Subcellular Location Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Isoform 1 and isoform 2 are expressed in liver, kidney, colon and small intestine. Isoform 1 but not isoform 2 is expressed in esophagus. {ECO:0000269|PubMed:18004212}.
Top Pathways Chemical carcinogenesis, Steroid hormone biosynthesis, Pentose and glucuronate interconversions, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450

Human UGT1A3 cDNA clone(NM_019093.2) - CDFG002268 from Creative Biomart

Species Human
Accession NM_019093.2

Human UGT1A3 ORF clone(NM_019093.2) - CDCL186679 from Creative Biomart

Species Human
Accession NM_019093.2

human UGT1A3 ORF clone - CDCH097978 from Creative Biomart

Species Human
Accession NM_019093

human UGT1A3 ORF clone - CDCH097979 from Creative Biomart

Species Human
Accession NM_019093

Human UGT1A3 ORF clone(NM_019093.2) - CDCR008516 from Creative Biomart

Species Human
Accession NM_019093.2

Human UGT1A3 ORF Clone(NM_019093.2) - CDCR304632 from Creative Biomart

Species Human
Accession NM_019093.2

Human UGT1A3 ORF Clone(NM_019093.2) - CDCR304633 from Creative Biomart

Species Human
Accession NM_019093.2

Human UGT1A3 ORF Clone(NM_019093.2) - CDCR304634 from Creative Biomart

Species Human
Accession NM_019093.2

Human UGT1A3 Gene cDNA Clone (full-length ORF Clone) - HG13314-G from Sino Biological

Species Human
Accession NM_019093.2

Human UGT1A3 ORF clone(NM_019093.2) - CDCL186679 from Creative biogene

Species Human

Human UGT1A3 cDNA Clone(NM_019093.2) - CDFG002268 from Creative biogene

Species Human
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