UGT1A3

Gene Symbol UGT1A3
Entrez Gene 54659
Alt Symbol UDPGT, UDPGT 1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C
Species Human
Gene Type protein-coding
Description UDP glucuronosyltransferase 1 family, polypeptide A3
Other Description UDP glycosyltransferase 1 family, polypeptide A3|UDP-glucuronosyltransferase 1-3|UDP-glucuronosyltransferase 1-C|UDP-glucuronosyltransferase 1A3|UGT1*3
Swissprots B8K287 P35503
Accessions AAA92020 AAG30423 AAL73500 AAL73501 AAL73502 AAT94066 AAY32612 AAY32613 AAY32614 AAY32615 AAY32616 AAY32617 AAY32618 AAY32619 AAY32620 AAY32621 AAY32622 AAY32623 AAY32624 AAY32625 ABD60346 ABD60347 BAD12517 BAD12518 BAD12519 BAD12520 EAW71060 P35503 AY435138 AAR95639 BC166641 AAI66641 DQ364248 ABC96772 NM_019093 NP_061966
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1. {ECO:0000269|PubMed:18674515}.
Subcellular Location Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Isoform 1 and isoform 2 are expressed in liver, kidney, colon and small intestine. Isoform 1 but not isoform 2 is expressed in esophagus. {ECO:0000269|PubMed:18004212}.
Top Pathways Chemical carcinogenesis, Steroid hormone biosynthesis, Pentose and glucuronate interconversions, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450

UGT1A3 CRISPR/Cas9 KO Plasmid (h) - sc-402839 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A3 HDR Plasmid (h) - sc-402839-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A3 Double Nickase Plasmid (h) - sc-402839-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A3 Double Nickase Plasmid (h2) - sc-402839-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A3 CRISPR Activation Plasmid (h) - sc-402839-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A3 CRISPR Activation Plasmid (h2) - sc-402839-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A3 Lentiviral Activation Particles (h) - sc-402839-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A3 Lentiviral Activation Particles (h2) - sc-402839-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A3 RNAi - H00054659-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU219141 from Sigma-Aldrich

Category siRNA
Prices $140.00, $140.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22458 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22458 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

UGT1A3 siRNA (Human) - CRJ0166 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UGT1A3 - MBS8238800 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human UGT1A3 (NM_019093.2) - SHH440072 from Creative biogene

Category siRNA
Species Reactivities Human

UGT1A3 shRNA Plasmid (Human) - CHJ0166 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

UGT1A3 miRNA 3'UTR clone - MiUTR1H-10990 from Creative biogene

Species Reactivities Human
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