Gene Symbol | UBE2L6 |
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Entrez Gene | 9246 |
Alt Symbol | RIG-B, UBCH8 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2L 6 |
Other Description | retinoic acid induced gene B protein|retinoic acid-induced gene B protein|ubiquitin carrier protein L6|ubiquitin-protein ligase L6|ubiquitin/ISG15-conjugating enzyme E2 L6 |
Swissprots | Q9UEZ0 A6NDM6 Q8N5D8 A8MY53 O14933 |
Accessions | CAB64566 EAW73755 EAW73756 EAW73757 EAW73758 EAW73759 O14933 AF031141 AAB86433 AF061736 AAD17525 AK093462 AK129621 AK226165 AK315755 BAG38109 BC032491 AAH32491 CR457126 CAG33407 DA097307 DQ891291 ABM82217 DQ894475 ABM85401 H17887 NM_004223 NP_004214 NM_198183 NP_937826 |
Function | Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3. {ECO:0000269|PubMed:15131269, ECO:0000269|PubMed:16428300, ECO:0000269|PubMed:20508617}. |
Tissue Specificity | Present in natural killer cells (at protein level). {ECO:0000269|PubMed:16709802}. |
Top Pathways | Ubiquitin mediated proteolysis |
UBE2L6-Over-expression-Lysate - LY13060a from Abgent, a WuXi AppTec company
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UBE2L6 293T Cell Transient Overexpression Lysate(Denatured) - H00009246-T01 from Acris Antibodies
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UBE2L6 overexpression lysate - LY401353 from Acris Antibodies
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UBE2L6 overexpression lysate - LY404883 from Acris Antibodies
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UBE2L6 293 Cell Lysate - 403465 from ABBIOTEC
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UBE2L6 293 Cell Lysate - 401236 from ABBIOTEC
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UbcH8/Ube2L6 Overexpression Lysate (Denatured) - H00009246-T01 from Novus Biologicals
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UbcH8/Ube2L6 Overexpression Lysate (Native) - NBL1-17539 from Novus Biologicals
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UbcH8/Ube2L6 Overexpression Lysate (Native) - NBL1-17538 from Novus Biologicals
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UBC8 (h): 293T Lysate - sc-114937 from Santa Cruz Biotechnology
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UBE2L6 Over-expression Lysate Product - GWB-676635 from Genway Biotech
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UBE2L6 Over-expression Lysate Product - GWB-5A2036 from Genway Biotech
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UbcH8/Ube2L6 Overexpression Lysate (Denatured) - H00009246-T02 from Novus Biologicals
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Panoply™ Human UBE2L6 Knockdown Stable Cell Line - CSC-DC016965 from Creative biogene
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