Gene Symbol | UBE2L6 |
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Entrez Gene | 9246 |
Alt Symbol | RIG-B, UBCH8 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2L 6 |
Other Description | retinoic acid induced gene B protein|retinoic acid-induced gene B protein|ubiquitin carrier protein L6|ubiquitin-protein ligase L6|ubiquitin/ISG15-conjugating enzyme E2 L6 |
Swissprots | Q9UEZ0 A6NDM6 Q8N5D8 A8MY53 O14933 |
Accessions | CAB64566 EAW73755 EAW73756 EAW73757 EAW73758 EAW73759 O14933 AF031141 AAB86433 AF061736 AAD17525 AK093462 AK129621 AK226165 AK315755 BAG38109 BC032491 AAH32491 CR457126 CAG33407 DA097307 DQ891291 ABM82217 DQ894475 ABM85401 H17887 NM_004223 NP_004214 NM_198183 NP_937826 |
Function | Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3. {ECO:0000269|PubMed:15131269, ECO:0000269|PubMed:16428300, ECO:0000269|PubMed:20508617}. |
Tissue Specificity | Present in natural killer cells (at protein level). {ECO:0000269|PubMed:16709802}. |
Top Pathways | Ubiquitin mediated proteolysis |
UBC8 (N-20) - sc-16196 from Santa Cruz Biotechnology
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UBC8 (k1H3) - sc-135629 from Santa Cruz Biotechnology
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Anti-Ube2L6 antibody - ab56502 from Abcam
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Anti-Ube2L6 antibody - ab98855 from Abcam
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Anti-Ube2L6 antibody [EPR4267(2)] - ab109086 from Abcam
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Anti-Ube2L6 antibody [K1H3] - ab115524 from Abcam
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Anti-UBE2L6 Antibody (aa1-152, clone K1H3) IHC-plus⢠- LS-B2964 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (aa38-87) - LS-C80540 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (aa1-152) - LS-C124754 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (aa124-153, AP) - LS-C272908 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (aa124-153, Biotin) - LS-C272910 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (aa124-153, APC) - LS-C272911 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (aa124-153, FITC) - LS-C272912 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (aa124-153, Azide-free, HRP) - LS-C272913 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (aa124-153, PE) - LS-C272915 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (C-Terminus) - LS-C107993 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (aa124-153) - LS-C326136 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (aa123-153) - LS-C99504 from LifeSpan Bioscience
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Anti-UBE2L6 Antibody (Internal, clone EPR4267(2)) - LS-C138198 from LifeSpan Bioscience
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UbcH8/Ube2L6 Antibody - NBP1-86885 from Novus Biologicals
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UbcH8/Ube2L6 Antibody - NBP1-55037 from Novus Biologicals
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UbcH8/Ube2L6 Antibody (k1H3) - NBP1-04351 from Novus Biologicals
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UbcH8/Ube2L6 Antibody - NBP1-55036 from Novus Biologicals
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UbcH8/Ube2L6 Antibody (2F12-1F4) - H00009246-M01 from Novus Biologicals
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UbcH8/Ube2L6 Antibody - H00009246-B01P from Novus Biologicals
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