UBE2L6

Gene Symbol	UBE2L6
Entrez Gene	9246
Alt Symbol	RIG-B, UBCH8
Species	Human
Gene Type	protein-coding
Description	ubiquitin-conjugating enzyme E2L 6
Other Description	retinoic acid induced gene B protein|retinoic acid-induced gene B protein|ubiquitin carrier protein L6|ubiquitin-protein ligase L6|ubiquitin/ISG15-conjugating enzyme E2 L6
Swissprots	Q9UEZ0 A6NDM6 Q8N5D8 A8MY53 O14933
Accessions	CAB64566 EAW73755 EAW73756 EAW73757 EAW73758 EAW73759 O14933 AF031141 AAB86433 AF061736 AAD17525 AK093462 AK129621 AK226165 AK315755 BAG38109 BC032491 AAH32491 CR457126 CAG33407 DA097307 DQ891291 ABM82217 DQ894475 ABM85401 H17887 NM_004223 NP_004214 NM_198183 NP_937826
Function	Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3. {ECO:0000269|PubMed:15131269, ECO:0000269|PubMed:16428300, ECO:0000269|PubMed:20508617}.
Tissue Specificity	Present in natural killer cells (at protein level). {ECO:0000269|PubMed:16709802}.
Top Pathways	Ubiquitin mediated proteolysis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

UBC8 CRISPR/Cas9 KO Plasmid (h) - sc-407024 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

UBC8 HDR Plasmid (h) - sc-407024-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

UBC8 Double Nickase Plasmid (h) - sc-407024-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

UBC8 Double Nickase Plasmid (h2) - sc-407024-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

UBC8 CRISPR Activation Plasmid (h) - sc-407024-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

UBC8 CRISPR Activation Plasmid (h2) - sc-407024-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

UBC8 Lentiviral Activation Particles (h) - sc-407024-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

UBC8 Lentiviral Activation Particles (h2) - sc-407024-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

UBC8 siRNA (h) - sc-41685 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

UBC8 shRNA Plasmid (h) - sc-41685-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

UBC8 shRNA (h) Lentiviral Particles - sc-41685-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

UbcH8/Ube2L6 RNAi - H00009246-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

UbcH8/Ube2L6 RNAi - H00009246-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU157291 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22372 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22372 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05912 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr05912

UBE2L6 siRNA (Human) - CRH6121 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

UBE2L6 - MBS8231699 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human UBE2L6 (NM_004223.4) - SHH439068 from Creative biogene Category siRNA Species Reactivities Human

Human UBE2L6 siRNA - orb266623 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

UBE2L6 shRNA Plasmid (Human) - CHH6121 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

UBE2L6 miRNA 3'UTR clone - MiUTR3H-06358 from Creative biogene Species Reactivities Human

UBE2L6 miRNA 3'UTR clone - MiUTR3H-06359 from Creative biogene Species Reactivities Human

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