JAG1

Gene Symbol	JAG1
Entrez Gene	182
Alt Symbol	AGS, AHD, AWS, CD339, HJ1, JAGL1
Species	Human
Gene Type	protein-coding
Description	jagged 1
Other Description	protein jagged-1
Swissprots	O15122 O14902 A0AV43 P78504 E9PCF9 Q15816 B4DYR1
Accessions	ACH41921 ACJ68516 ACJ68517 ACJ68518 EAX10341 P78504 AF003837 AAC51731 AF028593 AAB84053 AI268246 AK302554 BAG63823 AK312722 BAG35596 BC028007 BC098393 AAH98393 BC126205 AAI26206 BC126207 AAI26208 BF056748 HQ258535 ADR83289 U61276 AAB39007 U73936 AAC52020 U77720 AAC51323 U77914 AAC50909 Z50166 NM_000214 NP_000205
Function	Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro). {ECO:0000250, ECO:0000269|PubMed:18660822, ECO:0000269|PubMed:9462510}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells.
Top Pathways	Notch signaling pathway, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

JAG1 293T Cell Transient Overexpression Lysate(Denatured) - H00000182-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

JAG1 293 Cell Lysate - 400168 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Jagged 1 Overexpression Lysate (Denatured) - H00000182-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Jagged 1 Overexpression Lysate (Native) - NBL1-12091 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

JAG1 Over-expression Lysate Product - GWB-D58C20 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Human JAG1 / Jagged 1 / CD339 HEK293 Cell Lysate (WB positive control) - 11648-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human JAG1 / Jagged 1 / CD339 HEK293 Cell Lysate (WB positive control) - 11648-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human JAG1 Human Cells Transfected Lysate (positive control) (denatured) - orb173439 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human JAG1 Human Cells Transfected Lysate (positive control) (denatured) - orb173444 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human JAG1 Knockdown Stable Cell Line - CSC-DC007846 from Creative biogene Category Cell Line Species Human

JAG1 Knockout Cell Line-HeLa - CSC-RT1978 from Creative biogene Category Cell Line Species Human

JAG1 KO Cell Lysate-HeLa - CLKO-1838 from Creative biogene Category Cell Lysate

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