JAG1

Gene Symbol	JAG1
Entrez Gene	182
Alt Symbol	AGS, AHD, AWS, CD339, HJ1, JAGL1
Species	Human
Gene Type	protein-coding
Description	jagged 1
Other Description	protein jagged-1
Swissprots	O15122 O14902 A0AV43 P78504 E9PCF9 Q15816 B4DYR1
Accessions	ACH41921 ACJ68516 ACJ68517 ACJ68518 EAX10341 P78504 AF003837 AAC51731 AF028593 AAB84053 AI268246 AK302554 BAG63823 AK312722 BAG35596 BC028007 BC098393 AAH98393 BC126205 AAI26206 BC126207 AAI26208 BF056748 HQ258535 ADR83289 U61276 AAB39007 U73936 AAC52020 U77720 AAC51323 U77914 AAC50909 Z50166 NM_000214 NP_000205
Function	Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro). {ECO:0000250, ECO:0000269|PubMed:18660822, ECO:0000269|PubMed:9462510}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells.
Top Pathways	Notch signaling pathway, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Jagged1 peptide - ab94375 from Abcam Category Peptide

Human Jagged1 protein fragment - ab152171 from Abcam Category Protein Source Wheat germ Species Human

Human Jagged1 protein fragment - ab152172 from Abcam Category Protein Source Wheat germ Species Human

Human Jagged1 protein fragment - ab108575 from Abcam Category Protein Source HEK 293 cells Species Human

Mouse Jagged1 protein fragment - ab109346 from Abcam Category Protein Source HEK 293 cells Species Mouse

JAG1 / Jagged 1 Antibody Blocking Peptide - LS-E1444 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Jagged 1 Partial Recombinant Protein - H00000182-Q02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Jagged 1 Partial Recombinant Protein - H00000182-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Jagged 1 Protein - H00000182-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

JAG1-Antibody-C-term-Blocking-peptide - BP12146b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Jagged 1 Fc Chimera, CF - 1277-JG-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived

Human JAG1 His tag protein - orb83713 from Biorbyt Category Protein Prices $357.00, $527.00 Sizes 10 μg, 20 μg Source Human Species Human

Human JAG1 Fc tag protein - orb83708 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

JAG-1 (188-204) peptide - orb71720 from Biorbyt Category Peptide Prices $391.00 Sizes 5 mg

CD339 peptide - orb72480 from Biorbyt Category Peptide Prices $238.00 Sizes 500 µg

CD339 Blocking Peptide - 33R-10635 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

Human Jagged 1 Protein Protein - abx067571 from Abbexa Category Protein Source E.coli Species Human

Human Jagged 1 Protein Protein - abx067570 from Abbexa Category Protein Source E.coli Species Human

Human Jagged 1 Protein Protein - abx067572 from Abbexa Category Protein Source E.coli Species Human

CD339 / JAG1 - H00000182-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD339 / JAG1 - H00000182-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD339 / JAG1 - H00000182-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CD339 / JAG1 - H00000182-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

CD339 / JAG1 - H00000182-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CD339 / JAG1 - H00000182-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

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