| Gene Symbol |
MED7
|
| Entrez Gene |
9443
|
| Alt Symbol |
ARC34, CRSP33, CRSP9
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mediator complex subunit 7
|
| Other Description |
CRSP complex subunit 9|RNA polymerase transcriptional regulation mediator subunit 7 homolog|activator-recruited cofactor 34 kDa component|cofactor required for Sp1 transcriptional activation subunit 9|cofactor required for Sp1 transcriptional activation, subunit 9 (33kD)|cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa|mediator of RNA polymerase II transcription subunit 7|transcriptional coactivator CRSP33
|
| Swissprots |
O43513
|
| Accessions |
EAW61610 EAW61611 O43513 AF031383 AAC52115 AF104251 AAD12720 AK308393 AV711090 BC005250 BC006968 BQ011916 BQ130907 BT007368 AAP36032 CR457009 CAG33290 CR541696 CAG46497 NM_001100816 NP_001094286 NM_004270 NP_004261
|
| Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
|
| Subcellular Location |
Nucleus.
|
![Western Blot: MED7 Overexpression Lysate (Adult Normal) [NBL1-12994] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MED7.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/13117_MED7%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-12994-img0002.jpg)
![Western Blot: MED7 Overexpression Lysate (Adult Normal) [NBP2-09334] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MED7.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/16218_MED7%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-09334-img0001.jpg)