Gene Symbol | MED7 |
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Entrez Gene | 9443 |
Alt Symbol | ARC34, CRSP33, CRSP9 |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 7 |
Other Description | CRSP complex subunit 9|RNA polymerase transcriptional regulation mediator subunit 7 homolog|activator-recruited cofactor 34 kDa component|cofactor required for Sp1 transcriptional activation subunit 9|cofactor required for Sp1 transcriptional activation, subunit 9 (33kD)|cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa|mediator of RNA polymerase II transcription subunit 7|transcriptional coactivator CRSP33 |
Swissprots | O43513 |
Accessions | EAW61610 EAW61611 O43513 AF031383 AAC52115 AF104251 AAD12720 AK308393 AV711090 BC005250 BC006968 BQ011916 BQ130907 BT007368 AAP36032 CR457009 CAG33290 CR541696 CAG46497 NM_001100816 NP_001094286 NM_004270 NP_004261 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Subcellular Location | Nucleus. |
Med7 CRISPR/Cas9 KO Plasmid (h) - sc-417600 from Santa Cruz Biotechnology
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Med7 HDR Plasmid (h) - sc-417600-HDR from Santa Cruz Biotechnology
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Med7 Double Nickase Plasmid (h) - sc-417600-NIC from Santa Cruz Biotechnology
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Med7 Double Nickase Plasmid (h2) - sc-417600-NIC-2 from Santa Cruz Biotechnology
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Med7 CRISPR Activation Plasmid (h) - sc-417600-ACT from Santa Cruz Biotechnology
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Med7 CRISPR Activation Plasmid (h2) - sc-417600-ACT-2 from Santa Cruz Biotechnology
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Med7 Lentiviral Activation Particles (h) - sc-417600-LAC from Santa Cruz Biotechnology
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Med7 Lentiviral Activation Particles (h2) - sc-417600-LAC-2 from Santa Cruz Biotechnology
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Med7 siRNA (h) - sc-38581 from Santa Cruz Biotechnology
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Med7 shRNA Plasmid (h) - sc-38581-SH from Santa Cruz Biotechnology
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Med7 shRNA (h) Lentiviral Particles - sc-38581-V from Santa Cruz Biotechnology
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MED7 RNAi - H00009443-R01V from Novus Biologicals
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MED7 RNAi - H00009443-R01 from Novus Biologicals
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MISSION® esiRNA - EHU030411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13183 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13183 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01795 from Sigma-Aldrich
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MED7 siRNA (Human) - CRH6262 from Cohesion Biosciences
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shRNA set against Human MED7 (NM_004270.4) - SHH340143 from Creative biogene
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shRNA set against Human CRSP9(NM_004270.4) - SHH000847 from Creative biogene
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Human MED7 siRNA - orb266764 from Biorbyt
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MED7 shRNA Plasmid (Human) - CHH6262 from Cohesion Biosciences
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MED7 miRNA 3'UTR clone - MiUTR3H-07318 from Creative biogene
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MED7 miRNA 3'UTR clone - MiUTR3H-07319 from Creative biogene
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