Gene Symbol | MED7 |
---|---|
Entrez Gene | 9443 |
Alt Symbol | ARC34, CRSP33, CRSP9 |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 7 |
Other Description | CRSP complex subunit 9|RNA polymerase transcriptional regulation mediator subunit 7 homolog|activator-recruited cofactor 34 kDa component|cofactor required for Sp1 transcriptional activation subunit 9|cofactor required for Sp1 transcriptional activation, subunit 9 (33kD)|cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa|mediator of RNA polymerase II transcription subunit 7|transcriptional coactivator CRSP33 |
Swissprots | O43513 |
Accessions | EAW61610 EAW61611 O43513 AF031383 AAC52115 AF104251 AAD12720 AK308393 AV711090 BC005250 BC006968 BQ011916 BQ130907 BT007368 AAP36032 CR457009 CAG33290 CR541696 CAG46497 NM_001100816 NP_001094286 NM_004270 NP_004261 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Subcellular Location | Nucleus. |