ANXA2

Gene Symbol ANXA2
Entrez Gene 302
Alt Symbol ANX2, ANX2L4, CAL1H, HEL-S-270, LIP2, LPC2, LPC2D, P36, PAP-IV
Species Human
Gene Type protein-coding
Description annexin A2
Other Description annexin II|annexin-2|calpactin I heavy chain|calpactin I heavy polypeptide|calpactin-1 heavy chain|chromobindin 8|chromobindin-8|epididymis secretory protein Li 270|lipocortin II|placental anticoagulant protein IV|protein I
Swissprots Q8TBV2 Q6N0B3 Q567R4 Q9UDH8 Q96DD5 P07355
Accessions CAH59520 EAW77582 EAW77583 EAW77584 EAW77585 EAW77586 EAW77587 P07355 AA661718 AK092006 BAG52463 AK124427 AK222542 AK297923 BAG60240 AK309356 AW087150 BC001388 AAH01388 BC001748 BC009564 AAH09564 BC013843 BC015834 AAH15834 BC016774 AAH16774 BC021114 AAH21114 BC023990 AAH23990 BC052558 AAH52558 BC052567 AAH52567 BC066955 AAH66955 BC068065 AAH68065 BC093056 AAH93056 BT007432 AAP36100 BX640598 CAE45704 D00017 BAA00013 D28364 BAA05730 DQ891008 ABM81934 DQ894187 ABM85113 FJ224302 ACI45994 XM_011521475 XP_011519777 XM_011521476 XP_011519778 XM_011521477 XP_011519779 NM_001002857 NP_001002857 NM_001002858 NP_001002858 NM_001136015 NP_001129487 NM_004039 NP_004030
Function Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
Subcellular Location Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.

Annexin A2 (D11G2) Rabbit mAb - 8235 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D11G2
Western blot analysis of extracts from various cell lines using Annexin A2 (D11G2) Rabbit mAb (upper) and GAPDH (14C10) Rabbit mAb #2118 (lower).

Annexin II (3D5) - sc-47696 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Annexin II (3D5): sc-47696. Western blot analysis of Annexin II expression in non-transfected: sc-110760 (A) and human Annexin II transfected: sc-111344 (B) 293 whole cell lysates.

Annexin II (A-15) - sc-30757 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Annexin II (A-15): sc-30757. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

Annexin II (C-10) - sc-28385 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Annexin II (C-10): sc-28385. Immunoperoxidase staining of formalin fixed, paraffin-embedded human oral mucosa tissue showing membrane staining of surface epithelial cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Annexin II (H-50) - sc-9061 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Annexin II (H-50): sc-9061. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human skin showing membrane localization.

Annexin II (C-16) - sc-1924 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Annexin II (C-16): sc-1924. Western blot analysis of Annexin II expression in HeLa (A), K-562 (B), MDCK (C), NIH/3T3 (D) and KNRK (E) whole cell lysates.

Annexin II (D1/274.5) - sc-65873 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Annexin II (D1/274.5): sc-65873. Western blot analysis of Annexin II expression in non-transfected: sc-110760 (A) and human Annexin II transfected: sc-111344 (B) 293 whole cell lysates.

Annexin II (E-11) - sc-166762 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Annexin II (E-11): sc-166762. Western blot analysis of Annexin II expression in non-transfected 293T: sc-117752 (A), mouse Annexin II transfected 293T: sc-118430 (B), HeLa (C) and NIH/3T3 (D) whole cell lysates.

Annexin II (H-3) - sc-271175 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Annexin II (H-3): sc-271175. Western blot analysis of Annexin II expression in non-transfected: sc-117752 (A) and mouse Annexin II transfected: sc-118432 (B) 293T whole cell lysates.

Annexin II (H-5) - sc-48397 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Annexin II (H-5): sc-48397. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

Annexin II (K-13) - sc-30759 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

p-Annexin II (11.Tyr 24) - sc-135752 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of Annexin II phosphorylation in untreated (A, C), and lambda protein phosphatase treated (B, D) A-431 whole cell lysates. Antibodies tested include p-Annexin II (11.Tyr 24): sc-135752 (A, C) and Annexin II (H-50): sc-9061 (B, D).

p-Annexin II (85.Tyr 24) - sc-135753 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
p-Annexin II (85.Tyr 24): sc-135753. Western blot analysis of Annexin II phosphorylation in K-562 whole cell lysate.

Anti-Annexin A2 (phospho S26) antibody - ab192593 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Annexin A2 (phospho S26) antibody (ab192593) at 1/500 dilutionLane 1 : Extracts from HepG2 cellsLane 2 : Extracts from Jurkat cellsLane 3 : Extracts from K562 cellsLane 4 : Extracts from K562 cells with antigen-specific peptide

Anti-Annexin A2 antibody - ab41803 from Abcam

Prices $401.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Annexin A2 antibody (ab41803) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLane 3 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 4 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell Lysate Lane 5 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-Annexin A2 antibody - ab54771 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Annexin II antibody (ab54771) used in immunofluorescence at 10ug/ml on HeLa cells.

Anti-Annexin A2 antibody - ab154113 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Annexin A2 antibody (ab154113) at 1/1000 dilution + Rat2 whole cell lysate at 30 µg

Anti-Annexin A2 antibody - ab40943 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Annexin A2 antibody (ab40943) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lane 3 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-Annexin A2 antibody - ab66611 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Annexin A2 antibody - ab2242 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Annexin A2 antibody (ab2242) at 0.5 µg/ml + A431 lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-Annexin A2 antibody - ab90643 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Annexin A2 antibody (ab90643) at 1/500 dilutionLane 1 : SW480 cell lysateLane 2 : MDA-MB-231 cell lysate

Anti-Annexin A2 antibody [EPR13052(B)] - ab178677 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13052(B)
All lanes : Anti-Annexin A2 antibody [EPR13052(B)] (ab178677) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : SKBR-3 cell lysateLane 3 : K562 cell lysateLane 4 : HepG2 cell lysateLysates/proteins at 10 µg per lane.

Anti-Annexin A2 antibody [EPR13052(B)] (Alexa Fluor® 488) - ab200791 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13052(B)
ab200791 staining Annexin A2 in HeLa cells. The cells were fixed with 4% formaldehyde (10min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab200791 at 1/200 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at 2µg/ml (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Annexin A2 antibody [EPR13052(B)] (Alexa Fluor® 647) - ab200797 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13052(B)
ab200797 staining Annexin A2 in HeLa cells. The cells were fixed with 100% methanol (5min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab200797 at 1/200 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at 2µg/ml (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Annexin A2 antibody [EPR13053(2)(B)] - C-terminal - ab185957 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13053(2)(B)
All lanes : Anti-Annexin A2 antibody [EPR13053(2)(B)] - C-terminal (ab185957) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : 293 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
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