ID2

Gene Symbol	ID2
Entrez Gene	3398
Alt Symbol	GIG8, ID2A, ID2H, bHLHb26
Species	Human
Gene Type	protein-coding
Description	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
Other Description	DNA-binding protein inhibitor ID-2|DNA-binding protein inhibitor ID2|cell growth-inhibiting gene 8|class B basic helix-loop-helix protein 26|helix-loop-helix protein ID2|inhibitor of differentiation 2
Swissprots	Q02363
Accessions	AAY14810 EAX01018 EAX01019 Q02363 AK222682 BAD96402 AK311988 BAG34927 AY634687 AAV35470 BC030639 AAH30639 BE222494 D13891 BAA02990 DQ890858 ABM81784 DQ894013 ABM84939 M97796 AAA58681 NM_002166 NP_002157
Function	Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism. {ECO:0000269|PubMed:20861012}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:20861012}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:20861012}.
Tissue Specificity	Highly expressed in early fetal tissues, including those of the central nervous system.
Top Pathways	TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DNA-binding protein inhibitor ID-2 (ID2), Human, ELISA Kit - CSB-EL010967HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

DNA-binding protein inhibitor ID-2 (ID2), Human, ELISA Kit - E01D0300 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

ID2 (Human) Matched Antibody Pair - H00003398-AP21 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

DNA binding protein inhibitor ID 2 (ID2), ELISA Kit - MBS7214645 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

DNA-binding protein inhibitor ID-2, ELISA Kit - MBS282583 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA-binding protein inhibitor ID-2 (ID2), ELISA Kit - MBS7205669 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA-binding protein inhibitor ID-2 (ID2), ELISA Kit - MBS7206460 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA-binding protein inhibitor ID-2 (ID2), ELISA Kit - MBS7201624 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA-binding protein inhibitor ID-2 (ID2), ELISA Kit - MBS7200602 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA-binding protein inhibitor ID-2 (ID2), ELISA Kit - MBS7243880 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA-binding protein inhibitor ID-2 (ID2), ELISA Kit - MBS7208558 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA-binding protein inhibitor ID-2 (ID2), ELISA Kit - MBS7226533 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA-binding protein inhibitor ID-2 (ID2), ELISA Kit - MBS7207849 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA-binding protein inhibitor ID-2 (ID2), ELISA Kit - MBS7240911 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA-binding protein inhibitor ID-2 (ID2), ELISA Kit - MBS7216593 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA-binding protein inhibitor ID-2 (ID2), ELISA Kit - MBS7218672 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, ELISA Kit - MBS905830 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human ID2 is typically less than 5.88 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 23.5 pg/ml -1500 pg/ml.

Human DNA-binding protein inhibitor ID-2(ID2) ELISA kit - CSB-EL010967HU from Cusabio Category ELISA Kit Sensitivity 5.88pg/ml Range 23.5 pg/ml-1500 pg/ml

Human ID2 ELISA Kit - E012119 from Biobool Category ELISA Kit Sensitivity 0.1 ng/mL.

ID2 ELISA Kit (Human) (OKCA00659) - OKCA00659 from Aviva Systems Biology Category ELISA Kit Prices $590.00 Sizes 96 wells Sensitivity 5.88 pg/mL Range 23.5 pg/mL-1,500 pg/mL

anti-ID2 antibody - ARG53144 from Arigo Biolaboratories Category ELISA Kit

anti-ID2 antibody (Ready-to-Use) - ARG53145 from Arigo Biolaboratories Category ELISA Kit

DNA-binding protein inhibitor ID-2, ELISA Kit - MBS285809 from MyBioSource Category ELISA Kit Prices $425.00, $720.00, $3,160.00, $6,055.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human ID2 ELISA Kit - orb404326 from Biorbyt Category ELISA Kit Sensitivity 5.88pg/ml Range 23.5 pg/ml-1500 pg/ml

Search more