Gene Symbol | RTKN |
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Entrez Gene | 6242 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | rhotekin |
Other Description | - |
Swissprots | Q96PT6 Q9HB05 Q8WVN1 H7BXD4 Q9BST9 |
Accessions | EAW99674 EAW99675 EAW99676 Q9BST9 AF049227 AAL16767 AF290512 AAG01181 AK307302 AK308519 AK310036 AW410753 BC004558 AAH04558 BC017727 AAH17727 BG470092 BQ574374 BQ721791 DQ891471 ABM82397 EU176596 ABW03397 XM_005264478 XP_005264535 XM_005264479 XP_005264536 XR_939704 XR_939705 XR_939706 NM_001015055 NP_001015055 NM_001015056 NP_001015056 NM_033046 NP_149035 |
Function | Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures. {ECO:0000269|PubMed:10940294, ECO:0000269|PubMed:15480428, ECO:0000269|PubMed:16007136}. |
Tissue Specificity | Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested. Overexpressed in various cancer cell lines. {ECO:0000269|PubMed:10873388, ECO:0000269|PubMed:15480428}. |
Human RTKN protein fragment - ab90585 from Abcam
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RTKN / Rhotekin Antibody Blocking Peptide - LS-E20366 from LifeSpan Bioscience
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RTKN / Rhotekin Antibody Blocking Peptide - LS-E20367 from LifeSpan Bioscience
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Recombinant Human RTKN Protein - H00006242-Q01 from Novus Biologicals
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Rhotekin Blocking Peptide - 33R-3952 from Fitzgerald
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Rhotekin Blocking Peptide - 33R-2163 from Fitzgerald
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Rhotekin / RTKN - H00006242-Q01-10 from Acris Antibodies
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Rhotekin / RTKN - H00006242-Q01-25 from Acris Antibodies
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RTKN fusion protein - Ag3265 from Proteintech Group
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Recombinant Human Rhotekin, GST-tagged - RTKN-1147H from Creative Biomart
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Recombinant Human RTKN - RTKN-27494TH from Creative Biomart
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Recombinant Human RTKN, His-tagged - RTKN-27495TH from Creative Biomart
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Recombinant Human RTKN, His-tagged - RTKN-2460H from Creative Biomart
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Rho Assay Reagent (Rhotekin RBD, agarose), 650 µg - 14-383 from EMD Millipore
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Rhotekin, GST fusion protein, 500 µg - 14-662 from EMD Millipore
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Recombinant Human Rhotekin(RTKN) - CSB-YP020565HU CSB-EP020565HU CSB-BP020565HU CSB-MP020565HU from Cusabio
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Rhotekin Blocking Peptide - CBP4222 from Cohesion Biosciences
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Rhotekin Blocking Peptide - abx161433 from Abbexa
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Rhotekin / RTKN (transcript variant 2) - TP304517 from Acris Antibodies
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Rhotekin / RTKN (transcript variant 1) - TP318810 from Acris Antibodies
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Recombinant Human RTKN GST - CSI13800 from Cell Science
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Recombinant Rhotekin (RTKN) - RPC772Ra01 from Uscn Life Science Inc.
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RTKN Recombinant Protein Antigen - NBP1-88956PEP from Novus Biologicals
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RTKN Peptide, Human - M34GP13669H from Creative Peptides
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Recombinant Rhotekin (RTKN) - RPU50271 from Biomatik
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