RTKN

Gene Symbol RTKN
Entrez Gene 6242
Alt Symbol -
Species Human
Gene Type protein-coding
Description rhotekin
Other Description -
Swissprots Q96PT6 Q9HB05 Q8WVN1 H7BXD4 Q9BST9
Accessions EAW99674 EAW99675 EAW99676 Q9BST9 AF049227 AAL16767 AF290512 AAG01181 AK307302 AK308519 AK310036 AW410753 BC004558 AAH04558 BC017727 AAH17727 BG470092 BQ574374 BQ721791 DQ891471 ABM82397 EU176596 ABW03397 XM_005264478 XP_005264535 XM_005264479 XP_005264536 XR_939704 XR_939705 XR_939706 NM_001015055 NP_001015055 NM_001015056 NP_001015056 NM_033046 NP_149035
Function Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures. {ECO:0000269|PubMed:10940294, ECO:0000269|PubMed:15480428, ECO:0000269|PubMed:16007136}.
Tissue Specificity Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested. Overexpressed in various cancer cell lines. {ECO:0000269|PubMed:10873388, ECO:0000269|PubMed:15480428}.

Rhotekin (B-4) - sc-393833 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rhotekin (B-4): sc-393833. Western blot analysis of Rhotekin expression in non-transfected 293T: sc-117752 (A), human Rhotekin transfected 293T: sc-112761 (B), A-431 (C) and Jurkat (D) whole cell lysates.

Rhotekin (N-17) - sc-6220 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of rhotekin expression in HeLa (A,C) and Jurkat (B,D) whole cell lysates. Antibodies tested include Rhotekin (C-19): sc-6219 (A,B) and Rhotekin (N-17): sc-6220 (C,D).

Rhotekin (C-19) - sc-6219 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of rhotekin expression in HeLa (A,C) and Jurkat (B,D) whole cell lysates. Antibodies tested include Rhotekin (C-19): sc-6219 (A,B) and Rhotekin (N-17): sc-6220 (C,D).

Rhotekin (AA-18) - sc-100426 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Rhotekin (AA-18): sc-100426. Western blot analysis of Rhotekin expression in non-transfected: sc-117752 (A) and human Rhotekin transfected: sc-170213 (B) 293T whole cell lysates.

Rhotekin (H-252) - sc-366207 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-RTKN antibody - ab154954 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RTKN antibody (ab154954) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

Anti-RTKN antibody - ab57655 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
RTKN antibody (ab57655) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human colon.

Anti-RTKN antibody - ab91040 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RTKN antibody (ab91040) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µgSecondaryHRP-conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-RTKN antibody - ab90961 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RTKN antibody (ab90961) at 1 µg/ml (in 5% skim milk / PBS buffer) + Fetal liver lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-RTKN antibody [2E5] - ab115680 from Abcam

Prices $464.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2E5
Anti-RTKN antibody [2E5] (ab115680) at 1/500 dilution + A431 cell lysate

Anti-RTKN / Rhotekin Antibody (clone 1A4) - LS-C337804 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A4
IHC of paraffin-embedded Human endometrium tissue using anti-RTKN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-RTKN / Rhotekin Antibody (clone 2E9) - LS-C174147 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E9
IHC of paraffin-embedded Carcinoma of Human thyroid tissue using anti-RTKN mouse monoclonal antibody.

Anti-RTKN / Rhotekin Antibody (aa431-480) - LS-C111840 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RTKN antibody LS-C111840 Western blot of 293T cell lysate.

Anti-RTKN / Rhotekin Antibody (aa107-156) - LS-C111839 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RTKN antibody LS-C111839 Western blot of Fetal Liver lysate.

Anti-RTKN / Rhotekin Antibody - LS-C335700 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using RTKN antibody.

Anti-RTKN / Rhotekin Antibody (clone 2E5) IHC-plus™ - LS-B4410 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2E5
Anti-RTKN antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4410 concentration 10 ug/ml.

RTKN Antibody (2E5.) - H00006242-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E5.
Western Blot: RTKN Antibody (2E5) [H00006242-M01] - RTKN monoclonal antibody (M01), clone 2E5 Analysis of RTKN expression in A-431.

RTKN Antibody - NBP1-88956 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RTKN Antibody [NBP1-88956] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

RTKN Antibody - NBP2-20239 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RTKN Antibody [NBP2-20239] - Sample (30 ug of whole cell lysate) A: JurKat 7. 5% SDS PAGE gel, diluted at 1:1000.

RTKN Antibody - NBP1-54973 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RTKN Antibody [NBP1-54973] - Titration: 0.2-1 ug/ml, Positive Control: Human Liver.

RTKN Antibody - H00006242-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: RTKN Antibody [H00006242-A01] - RTKN polyclonal antibody (A01), Lot # 060525JCS1. Western Blot analysis of RTKN expression in A-431.

Monoclonal Anti-RTKN antibody produced in mouse - WH0006242M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E5
<B>Immunoblotting</B><BR/>Monoclonal Anti-RTKN, <B>Cat. No. WH0006242M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~62.6 kDa using A-431 lysate.

Anti-RTKN (376-390) antibody produced in rabbit - SAB1100409 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-RTKN (376-390) : <B>Cat. No. SAB1100409</B>: Immunofluorescence of HUVEC cells using RTKN (376-390) , Cat. No. SAB1100409 (red) at a 1:400 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-RTKN (117-130) antibody produced in rabbit - SAB1100408 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-RTKN (117-130) : <B>Cat. No. SAB1100408</B>: Immunofluorescence of HUVEC cells using RTKN (117-130) , Cat. No. SAB1100408 (red) at a 1:100 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-RTKN, (N-terminal) antibody produced in rabbit - SAB2104164 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RTKN, antibody produced in rabbit: <B>Cat. No. SAB2104164</B>: Immunoblotting analysis of RTKN in fetal liver tissue lysate with RTKN anitbody at 1 μg/mL.
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